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从软蜱(科氏钝缘蜱)中分离出一种螺旋体:一种可能导致牛流行流产的病原体。

Isolation of a spirochete from the soft tick, Ornithodoros coriaceus: a possible agent of epizootic bovine abortion.

作者信息

Lane R S, Burgdorfer W, Hayes S F, Barbour A G

出版信息

Science. 1985 Oct 4;230(4721):85-7. doi: 10.1126/science.3898367.

DOI:10.1126/science.3898367
PMID:3898367
Abstract

A Borrelia-like spirochete was detected in all three parasitic stages of Ornithodoros coriaceus, the soft tick implicated in the epizoology of epizootic bovine abortion. After the spirochete had been isolated, its distinctness from other North American tick-borne borreliae as well as from Spirochaeta aurantia, Treponema pallidum, and Leptospira interrogans serovar pomona was established on the basis of its morphology, protein components, and inability to infect mice. The spirochete is passed trans-stadially and via eggs by ticks, and it is also excreted in coxal fluid after ticks have fed and detached. Circumstantial evidence suggests that the spirochete may be causally related to epizootic bovine abortion.

摘要

在革蜱(Ornithodoros coriaceus)的所有三个寄生阶段均检测到一种类似疏螺旋体的螺旋体,这种软蜱与牛流行热流产的流行病学有关。分离出该螺旋体后,基于其形态、蛋白质成分以及无法感染小鼠,确定了它与其他北美蜱传疏螺旋体以及与金黄螺旋体、梅毒螺旋体和波摩那群问号钩端螺旋体的差异。该螺旋体可经蜱的各发育阶段和卵传播,蜱吸血并脱落后,还会通过基节液排出。间接证据表明,该螺旋体可能与牛流行热流产存在因果关系。

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1
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引用本文的文献

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Transovarial Transmission of by Its Tick Vector and Reservoir Host .
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Pathogenesis of Relapsing Fever.回归热的发病机制。
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Perpetuation of Borreliae.螺旋体的持续存在。
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Corrigendum: Differential Expression of Putative Defensins Mediated by Tick Feeding.勘误:蜱虫取食介导的假定防御素的差异表达。
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