Bourlond Baudouin, Maurizi Niccolo, Antiochos Panagiotis, Skalidis Ioannis, Auf Der Springe Katarina, Royer Claire, Monney Pierre, Muller Olivier, Kirsch Mathias
Department of Cardiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Front Cardiovasc Med. 2024 Jun 25;11:1378333. doi: 10.3389/fcvm.2024.1378333. eCollection 2024.
Primary cardiac tumors remain exceptionally rare, characterized by a poor prognosis. Among them, sarcomas originating in the pulmonary arteries constitute the most infrequent subgroup within primary cardiac sarcomas.
This report presents the case of a 76-year-old female experiencing a recurrence of an undifferentiated pleomorphic intracardiac pulmonary artery sarcoma located in the right ventricular outflow tract, manifesting 8 years after initial remission. Successful outcomes were attained through a combination of surgical resection, state-of-the-art radiotherapy, and chemotherapy. This comprehensive approach proved essential for optimizing both survival and quality of life.
The unexpectedly prolonged recurrence-free survival observed in this case underscores the effectiveness of the comprehensive multimodal treatment approach outlined in the existing literature. This highlights the pivotal role of a multidisciplinary strategy in addressing primary cardiac sarcomas, particularly those arising in the pulmonary arteries.
原发性心脏肿瘤仍然极为罕见，预后较差。其中，起源于肺动脉的肉瘤是原发性心脏肉瘤中最罕见的亚组。
本报告介绍了一名76岁女性的病例，该患者右心室流出道出现未分化多形性心内肺动脉肉瘤复发，初次缓解8年后出现症状。通过手术切除、先进的放疗和化疗相结合，取得了成功的治疗效果。这种综合治疗方法被证明对于优化生存率和生活质量至关重要。
该病例中观察到的意外延长的无复发生存期强调了现有文献中概述的综合多模式治疗方法的有效性。这突出了多学科策略在治疗原发性心脏肉瘤，特别是起源于肺动脉的肉瘤方面的关键作用。
