Development. 2024 Jul 1;151(13). doi: 10.1242/dev.204215. Epub 2024 Jul 10.
Germ granules have been hypothesized to deliver mRNAs of germ cell fate determinants to primordial germ cells. Now, a new study in Development finds that many mRNAs enriched in germ granules are not involved in germline development in Caenorhabditis elegans. To find out more about the story behind the paper, we caught up with first author Alyshia Scholl, second author Yihong Liu and corresponding author Geraldine Seydoux, Professor at Johns Hopkins University School of Medicine.
人们推测生殖质能够将生殖细胞命运决定因子的 mRNA 运送到原始生殖细胞。现在,《发育》杂志的一项新研究发现,在秀丽隐杆线虫中,许多富含生殖质的 mRNA 并不参与生殖系发育。为了更多地了解这篇论文背后的故事,我们采访了第一作者 Alyshia Scholl、第二作者 Yihong Liu 和通讯作者 Geraldine Seydoux,他们均为约翰霍普金斯大学医学院的教授。