Dipartimento Ambiente e Salute, Istituto Superiore di Sanità, Rome, Italy.
Unità Operativa Complessa di Patologia Clinica, Dipartimento dei Servizi e delle Scienze Radiologiche, Ospedale Sant'Antonio Abate, Azienda Sanitaria Provinciale di Trapani, Trapani, Italy.
Ann Ist Super Sanita. 2024 Apr-Jun;60(2):118-125. doi: 10.4415/ANN_24_02_06.
A pooled study on Italian asbestos cement plant cohorts observed mortality risk for asbestos-related diseases. This study analysed the mortality of workers cohort of an asbestos cement plant in Syracuse, Italy.
Workers' vital status and causes of death, during 1970-2018, were identified in regional health databases. Standardized mortality ratios (SMRs) by sex and temporal variables were calculated.
Of the 900 cohort's subjects (636 men, 259 women, 5 unknown sex), for 867 the vital ascertainment was possible: 505 died during study period. All-cause mortality is similarly to the expected among men and lower among women. Pleural and lung malignant neoplasms (MN) exceeded in men (SMR=27.1, SMR=1.95), retroperitoneal and peritoneal MN in both sexes, no cases of larynx MN were observed. Mortality excess for ovarian MN (SMR=1.5) and asbestosis in both sexes (men: SMR=431.9, women: SMR=116.6) were found.
Exceeding mortality from asbestos-related diseases, particularly in men was highlighted.
一项针对意大利石棉水泥厂队列的汇总研究观察到了与石棉相关疾病的死亡风险。本研究分析了意大利锡拉库萨一家石棉水泥厂工人队列的死亡率。
在区域卫生数据库中确定了 1970 年至 2018 年期间工人的生命状态和死因。按性别和时间变量计算了标准化死亡率（SMR）。
在该队列的 900 名受试者中（636 名男性，259 名女性，5 名未知性别），对 867 名受试者的生命状态进行了确定：在研究期间有 505 人死亡。男性的全因死亡率与预期相似，女性的死亡率较低。胸膜和肺部恶性肿瘤（MN）在男性中更为常见（SMR=27.1，SMR=1.95），腹膜后和腹膜 MN 在两性中均有发生，喉 MN 无病例。观察到卵巢 MN（SMR=1.5）和两性石棉肺的死亡率过高（男性：SMR=431.9，女性：SMR=116.6）。
突出显示了与石棉相关的疾病导致的死亡率过高，特别是在男性中。
