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解析复杂关系——心房颤动与肺动脉高压。

Unraveling the Complex Relationship-Atrial Fibrillation and Pulmonary Hypertension.

机构信息

Dayanand Medical College, Punjab, India.

Sri Devaraj Urs Medical College, Kolar, Karnataka, India.

出版信息

Curr Cardiol Rep. 2024 Sep;26(9):885-891. doi: 10.1007/s11886-024-02089-4. Epub 2024 Jul 10.

DOI:10.1007/s11886-024-02089-4
PMID:38985227
Abstract

PURPOSE OF REVIEW

In this article, we underscore the importance of identifying risk factors and monitoring pulmonary hypertension patients for signs of arrhythmias, as this proactive approach can reduce morbidity and mortality.

RECENT FINDINGS

Atrial fibrillation is the most prevalent among cardiac arrhythmias and is associated with an increased risk of stroke, morbidity, and mortality. Smoking, obesity, hypertension, a sedentary lifestyle, and diabetes mellitus are some of the modifiable risk factors for atrial fibrillation. Recent studies show that the risk of atrial fibrillation is rising in patients with parenchymal and vascular lung disease. Stretching in the atria and pulmonary veins may lead to the onset of atrial fibrillation in cardiac conditions like hypertension, heart failure, and valvular disease. Atrial fibrillation in patients with pulmonary hypertension (PH) denotes a more advanced disease. Patients with PH are more susceptible to hemodynamic stress caused by tachycardia and an uncoordinated atrioventricular contraction. Therefore, atrial arrhythmias need to be treated because inadequate control of cardiac arrhythmias may result in poor clinical outcomes and lead to disease progression in PH patients. Aside from being a sign of severe disease, AF can also speed up and exacerbate the condition.

摘要

目的综述

本文强调了识别风险因素和监测肺动脉高压患者心律失常迹象的重要性,因为这种积极主动的方法可以降低发病率和死亡率。

最新发现

心房颤动是最常见的心律失常之一,与中风、发病率和死亡率增加有关。吸烟、肥胖、高血压、 sedentary lifestyle 和糖尿病等是心房颤动的一些可改变的危险因素。最近的研究表明,在实质和血管性肺疾病患者中,心房颤动的风险正在上升。在高血压、心力衰竭和瓣膜病等心脏疾病中,心房的伸展和肺静脉可能导致心房颤动的发生。肺动脉高压 (PH) 患者的心房颤动表示疾病更严重。PH 患者更容易受到心动过速和不协调的房室收缩引起的血流动力学应激。因此,需要治疗房性心律失常,因为心律失常控制不当可能导致不良临床结局,并导致 PH 患者的疾病进展。除了是严重疾病的标志外,AF 还可以加速和加重病情。

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本文引用的文献

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Pulm Circ. 2020 Mar 9;10(1):2045894020910685. doi: 10.1177/2045894020910685. eCollection 2020 Jan-Mar.
2
[Tachycardia and pulmonary arterial hypertension].[心动过速与肺动脉高压]
Herzschrittmacherther Elektrophysiol. 2020 Mar;31(1):33-38. doi: 10.1007/s00399-020-00668-w. Epub 2020 Feb 11.
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<Editors' Choice> Pulmonary Hypertension: Diagnosis, Management, and Treatment.<编辑推荐> 肺动脉高压:诊断、管理与治疗
Nagoya J Med Sci. 2019 Feb;81(1):19-30. doi: 10.18999/nagjms.81.1.19.
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The correlation of pulmonary arterial hypertension with late recurrence of paroxysmal atrial fibrillation after catheter ablation.肺动脉高压与导管消融术后阵发性心房颤动晚期复发的相关性。
J Thorac Dis. 2018 May;10(5):2789-2794. doi: 10.21037/jtd.2018.04.92.
5
Combination therapy in pulmonary arterial hypertension: recent accomplishments and future challenges.肺动脉高压的联合治疗:近期成果与未来挑战
Pulm Circ. 2017 Apr-Jun;7(2):312-325. doi: 10.1177/2045893217710639. Epub 2017 May 30.
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The current approach of atrial fibrillation management.目前房颤的管理方法。
Avicenna J Med. 2016 Jan-Mar;6(1):8-16. doi: 10.4103/2231-0770.173580.
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Supraventricular Arrhythmias in Patients With Pulmonary Arterial Hypertension.肺动脉高压患者的室上性心律失常
Am J Cardiol. 2015 Dec 15;116(12):1883-9. doi: 10.1016/j.amjcard.2015.09.039. Epub 2015 Oct 9.
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Pharmacological therapy for patients with chronic thromboembolic pulmonary hypertension.慢性血栓栓塞性肺动脉高压患者的药物治疗
Eur Respir Rev. 2015 Jun;24(136):272-82. doi: 10.1183/16000617.00001015.
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Updated clinical classification of pulmonary hypertension.肺动脉高压的最新临床分类。
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