Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia (Dr Bertumen); California Department of Public Health, Richmond, California (Drs Bertumen and Pascopella, Mss Han and Glenn-Finer, Dr McElroy, Ms Stockman, and Dr Barry); Stanford University School of Medicine, Palo Alto, California (Dr Wong); Alameda County Public Health Department, San Leandro, California (Dr Chitnis); University of California, San Francisco School of Medicine, San Francisco, California (Dr Jaganath); and Los Angeles County Public Health Department, Los Angeles, California (Ms Jewell and Dr Gounder).
J Public Health Manag Pract. 2024;30(5):728-732. doi: 10.1097/PHH.0000000000001955. Epub 2024 Jul 22.
Epidemiologic data regarding persons with active tuberculosis (TB) and chronic hepatitis B virus (cHBV) infection are limited because of lack of routine surveillance of cHBV in persons with TB. Potential underdiagnosis of cHBV in California among those with TB is concerning. We matched TB and cHBV registries to identify cHBV infections among persons diagnosed with TB during 2016-2020 and described their demographic characteristics. We calculated expected cHBV cases among persons with TB for each demographic characteristic using published cHBV prevalence estimates for the locations of birth for persons with TB. Estimates were from general or emigrant adult and teen populations. Reported cHBV infection among persons with TB were 23% lower than expected, particularly among Asian persons, persons living in the two healthiest Healthy Places Index quartiles, and residents of less populated jurisdictions in California. Results show the possibility exists for underdiagnosis of cHBV in persons with TB in California.
有关活动性肺结核 (TB) 和慢性乙型肝炎病毒 (cHBV) 感染者的流行病学数据因缺乏对 TB 患者 cHBV 的常规监测而受到限制。在加利福尼亚州,TB 患者中 cHBV 的潜在漏诊令人担忧。我们将 TB 和 cHBV 登记处进行匹配,以确定在 2016-2020 年期间被诊断为 TB 的患者中的 cHBV 感染情况,并描述了他们的人口统计学特征。我们使用为 TB 患者的出生地位置发布的 cHBV 流行率估计值,为具有 TB 的个体的每种人口统计学特征计算了预期的 cHBV 病例。估计值来自一般或移民成年人和青少年人群。报告的 TB 患者中的 cHBV 感染率比预期低 23%,尤其是在亚洲人、居住在两个最健康的健康状况指数四分位数内的人和加利福尼亚州人口较少的司法管辖区的居民中。结果表明,在加利福尼亚州,TB 患者中可能存在 cHBV 的漏诊情况。