Department of Radiology, Liaocheng People's Hospital, Liaocheng, China.
Department of Pathology, Liaocheng People's Hospital, Liaocheng, China.
World Neurosurg. 2024 Oct;190:53-55. doi: 10.1016/j.wneu.2024.07.017. Epub 2024 Jul 8.
Epidermoid cysts are prevalent noncancerous cutaneous lesions known to exhibit unusually extended periods of growth. In this study, we present a remarkable case of an epidermoid cyst located on the scalp, which exhibited a growth period of 76 years, the longest growth time documented in the literature to date. The presence of the mass was noted at birth, and it exhibited gradual growth throughout the years, with a notable acceleration observed during the final 2 years. The patient underwent a surgical excision, and the histopathological analysis was consistent with epidermoid cyst, featuring localized rupture and demonstrating foreign body granulomatous inflammation. This case highlights the ability of epidermoid cysts to manifest as slow-growing entities over an exceptionally prolonged timeframe. Furthermore, instances of rapid growth may be attributed to a combination of mass rupture and inflammatory processes.
表皮样囊肿是一种常见的非癌性皮肤病变，其生长周期异常延长。本研究报告了一例位于头皮的表皮样囊肿，其生长周期长达 76 年，是迄今为止文献中记录到的最长生长时间。该肿块在出生时即被发现，此后多年逐渐生长，最后 2 年生长速度明显加快。患者接受了手术切除，组织病理学分析符合表皮样囊肿，表现为局部破裂，并伴有异物巨细胞肉芽肿性炎症。本病例突出了表皮样囊肿在异常长的时间内表现为缓慢生长实体的能力。此外，快速生长的情况可能归因于肿块破裂和炎症过程的共同作用。
