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对油橄榄花粉的过敏反应:皮肤点刺试验、放射变应原吸附试验、酶联免疫吸附测定和支气管激发试验之间的关系。

Allergy to Olea europaea pollen: relationship between skin prick tests, RAST, ELISA and bronchial provocations tests.

作者信息

Melillo G, D'Amato G, Liccardi G, D'Agostino F, Schiano M

出版信息

Allergol Immunopathol (Madr). 1985 May-Jun;13(3):229-34.

PMID:3898790
Abstract

Olea Europaea is the most important allergenic tree in Southern Italy and in the Naples area. Its pollination period lasts from the middle of April to the end of June. In our pollinosis patients we observed frequency of sensitization of 13.05% to Olea pollen. That means that this pollen follows Parietaria (47.80%) and Gramineae (34.70%) regarding the frequency of allergic sensitization. In an attempt to evaluate the degree of allergic sensitization to Olea pollen and the concordance of various tests, we studied 24 asthmatic patients with skin positivity to only this pollen using commercially available allergen extracts and reagents. The patients were examined by SPT, RAST, ELISA and BPT with allergen. Our study has shown that there is no relationship between the results of SPT and Phadebas RAST; a slight relationship between SPT and Phadezym RAST, and a very good relationship between Phadebas and Phadezym RAST. Bronchial challenge with Olea extract was positive in all patients. These results may be interpreted considering the low degree of purification of Olea pollen extracts available commercially.

摘要

油橄榄是意大利南部和那不勒斯地区最重要的致敏树木。其授粉期从4月中旬持续到6月底。在我们的花粉症患者中,我们观察到对油橄榄花粉的致敏频率为13.05%。这意味着就过敏致敏频率而言,这种花粉仅次于墙草(47.80%)和禾本科(34.70%)。为了评估对油橄榄花粉的过敏致敏程度以及各种检测方法的一致性,我们使用市售过敏原提取物和试剂,对24例仅对这种花粉皮肤检测呈阳性的哮喘患者进行了研究。通过皮肤点刺试验(SPT)、放射变应原吸附试验(RAST)、酶联免疫吸附测定(ELISA)和过敏原支气管激发试验(BPT)对患者进行检查。我们的研究表明,皮肤点刺试验结果与法德巴斯放射变应原吸附试验结果之间没有关系;皮肤点刺试验与法德齐姆放射变应原吸附试验之间有轻微关系,法德巴斯放射变应原吸附试验与法德齐姆放射变应原吸附试验之间有非常好的关系。用橄榄提取物进行支气管激发试验,所有患者均呈阳性。考虑到市售油橄榄花粉提取物的纯化程度较低,这些结果或许可以得到解释。

相似文献

1
Allergy to Olea europaea pollen: relationship between skin prick tests, RAST, ELISA and bronchial provocations tests.对油橄榄花粉的过敏反应:皮肤点刺试验、放射变应原吸附试验、酶联免疫吸附测定和支气管激发试验之间的关系。
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Allergol Immunopathol (Madr). 1995 Jan-Feb;23(1):41-6.
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