Liccardi G, Russo M, Saggese M, D'Amato M, D'Amato G
Department of Chest Diseases, Hospital A. Cardarelli.
Allergol Immunopathol (Madr). 1995 Jan-Feb;23(1):41-6.
In the last few years an increasing interest for Olea europaea (O.e.) pollen has been developed in many countries. Several authors have studied the aerobiological, allergenic, epidemiological and clinical features of this pollinosis. The aim of our study was to evaluate cutaenous and serological responses to other oleaceae pollens allergens (Ligustrum vulgare (L.v.) and Fraxinus excelsior (F.e.) in patients with skin positivity to Olea europaea pollen extract. Twenty-three atopic rhinitis and/or asthmatic patients living in Naples area and with immediate positive skin reaction only to O.e. pollen extract were examined. Patients were tested by skin prick test (SPT) for O.e., F.e. and L.v. with glycerinated allergenic extracts. Serum enzyme immunoassay for the same allergens was also performed. We found a statistically significant correlation between the results of SPT and of specific IgE assay for Oleaceae pollens as well as between the results of the in vivo vs in vitro tests. We suggests the utility, in patients with O.e. pollinosis who travel in Northern europe, to plan SPT and/or specific IgE determinations also with F.e. and L.v. allergenic extracts for the possibility of developing a nasal and/or bronchial symptomatology after the inhalation of these pollen grains.
在过去几年中,许多国家对油橄榄(O.e.)花粉的兴趣日益浓厚。几位作者研究了这种花粉症的空气生物学、致敏性、流行病学和临床特征。我们研究的目的是评估对油橄榄花粉提取物皮肤呈阳性反应的患者对其他木犀科花粉过敏原(欧洲女贞(L.v.)和欧洲白蜡树(F.e.))的皮肤和血清学反应。对23名居住在那不勒斯地区、仅对油橄榄花粉提取物皮肤即刻呈阳性反应的特应性鼻炎和/或哮喘患者进行了检查。用甘油化变应原提取物通过皮肤点刺试验(SPT)对患者进行油橄榄、欧洲白蜡树和欧洲女贞检测。还对相同变应原进行了血清酶免疫测定。我们发现木犀科花粉的皮肤点刺试验结果与特异性IgE检测结果之间以及体内试验与体外试验结果之间存在统计学上的显著相关性。我们建议,对于在北欧旅行的油橄榄花粉症患者,也应计划用欧洲白蜡树和欧洲女贞变应原提取物进行皮肤点刺试验和/或特异性IgE测定,因为吸入这些花粉颗粒后有可能出现鼻部和/或支气管症状。