Kamylla Guimarães Garcia, MS, School of Dentistry, University of Ribeirão Preto, Ribeirão Preto, Brazil.
Gabriel Pereira Nunes, PhD student, Department of Preventive and Restorative Dentistry, School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil.
Oper Dent. 2024 Jul 1;49(4):465-474. doi: 10.2341/24-002-L.
This in vitro study aimed to assess the impact of incorporating calcium glycerophosphate (CaGP) and sodium fluoride (NaF) in addition to 35% hydrogen peroxide concerning the enamel mechanical and morphological properties.
Specimens of bovine enamel were chosen based on their initial surface hardness (SHi) and subsequently divided into five gel groups (n=12): 1) 35% Hydrogen Peroxide (HP) Gel; 2) HP + 0.1% NaF Gel (HP/NaF); 3) HP + 0.25% CaGP Gel (HP/CaGP); 4) HP + 0.1% NaF + 0.25% CaGP Gel (HP/NaF/CaGP) and 5) HP Blue 35% Gel (HP Blue). The bleaching gels were applied thrice, for 40 min, at intervals of 7 days each. After 21 days, the final surface hardness (SHf), integrated hardness (IH), Polydispersity Index (PdI) and Zeta Potential (Zp), surface roughness (Ra, after and before), and surface/structural analysis by Scanning Electron Microscopy (SEM) were determined. The data were submitted to ANOVA (one-way and two-way) followed by the Student-Newman-Keuls test (α=0.05).
The addition of NaF to HP reduced demineralization by 11.5% in relation to HP (p<0.05). The NaF/CaGP association reduction is 22.8 and 20% higher in comparison to HP/NaF/CaGP and HP Blue, respectively. The IH when the PH/NaF/CaGP bleaching gel was applied, was 14% higher compared to HP and HP Blue groups.
It can be concluded that the association of NaF and CaGP with the 35% hydrogen peroxide gel (HP/NaF/CaGP) significantly changed tooth enamel demineralization in terms of surface, depth, roughness, and enamel morphology.
本体外研究旨在评估在 35%过氧化氢中加入甘油磷酸钙（CaGP）和氟化钠（NaF）对牙釉质机械和形态特性的影响。
根据初始表面硬度（SHi）选择牛牙釉质标本，然后将其分为五组凝胶（n=12）：1）35%过氧化氢凝胶（HP）；2）HP+0.1%NaF 凝胶（HP/NaF）；3）HP+0.25%CaGP 凝胶（HP/CaGP）；4）HP+0.1%NaF+0.25%CaGP 凝胶（HP/NaF/CaGP）和 5）HP Blue 35%凝胶（HP Blue）。漂白凝胶应用 3 次，每次 40 分钟，间隔 7 天。21 天后，测定最终表面硬度（SHf）、整体硬度（IH）、多分散指数（PdI）和 Zeta 电位（Zp）、表面粗糙度（Ra，处理前后）以及扫描电子显微镜（SEM）的表面/结构分析。数据采用单因素和双因素方差分析（one-way and two-way），然后采用 Student-Newman-Keuls 检验（α=0.05）。
与 HP 相比，HP 中加入 NaF 使脱矿减少 11.5%（p<0.05）。与 HP/NaF/CaGP 和 HP Blue 相比，NaF/CaGP 结合物的减少率分别高 22.8%和 20%。与 HP 和 HP Blue 组相比，应用 PH/NaF/CaGP 漂白凝胶时，IH 增加了 14%。
可以得出结论，NaF 和 CaGP 与 35%过氧化氢凝胶（HP/NaF/CaGP）的联合应用显著改变了牙釉质的脱矿作用，包括表面、深度、粗糙度和牙釉质形态。
