Kingsley A N
Am Surg. 1985 Sep;51(9):545-7.
Two hundred and forty-nine patients are divided into four homogenous groups to compare the efficacy of Cimetidine versus antacids, as well as the mode of delivery--bolus versus continuous drip--in the prophylaxis of acute hemorrhagic gastritis in critically ill patients. Antacids were favored over Cimetidine, and the continuous drip was the superior method with both drugs.
249名患者被分为4个同质组,以比较西咪替丁与抗酸剂的疗效,以及给药方式——大剂量推注与持续滴注——对危重症患者急性出血性胃炎的预防效果。结果显示,抗酸剂比西咪替丁更具优势,且两种药物采用持续滴注的方式效果更佳。