大肠杆菌菌血症、脑膜炎和血色素沉着症。
Escherichia coli bacteremia, meningitis, and hemochromatosis.
作者信息
Christopher G W
出版信息
Arch Intern Med. 1985 Oct;145(10):1908.
PMID:3899040
Abstract
A 67-year-old man with Escherichia coli bacteremia and meningitis was found to have hemochromatosis. To my knowledge this is the first documented case of E coli meningitis occurring in the setting of hemochromatosis. The case raises issues regarding the role of chronic liver disease in the pathogenesis of gram-negative sepsis and the impact of iron loading on host immunocompetence and bacterial virulence.
摘要
一名67岁患有大肠杆菌菌血症和脑膜炎的男性被发现患有血色素沉着症。据我所知，这是首例有记录的在血色素沉着症背景下发生的大肠杆菌脑膜炎病例。该病例引发了关于慢性肝病在革兰氏阴性菌败血症发病机制中的作用以及铁负荷对宿主免疫能力和细菌毒力影响的问题。
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