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老年护理机构抗生素使用中的分配正义与价值权衡

Distributive justice and value trade-offs in antibiotic use in aged care settings.

作者信息

Williams Jane, Chawraingern Sittichoke, Degeling Chris

机构信息

Australian Centre for Health Engagement, Evidence and Values (ACHEEV), School of Health and Society, University of Wollongong, Wollongong, Australia.

Sydney Health Ethics, School of Public Health, The University of Sydney, Sydney, Australia.

出版信息

Monash Bioeth Rev. 2024 Dec;42(Suppl 1):41-50. doi: 10.1007/s40592-024-00191-5. Epub 2024 Jul 11.

DOI:10.1007/s40592-024-00191-5
PMID:38990508
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11850501/
Abstract

Residential aged care facilities (RACF) are sites of high antibiotic use in Australia. Misuse of antimicrobial drugs in RACF contributes to antimicrobial resistance (AMR) burdens that accrue to individuals and the wider public, now and in the future. Antimicrobial stewardship (AMS) practices in RACF, e.g. requiring conformation of infection, are designed to minimise inappropriate use of antibiotics. We conducted dialogue groups with 46 participants with a parent receiving aged care to better understand families' perspectives on antibiotics and care in RACF. Participants grappled with value trade offs in thinking about their own parents' care, juggling imagined population and future harms with known short term comfort of individuals and prioritising the latter. Distributive justice in AMR relies on collective moral responsibility and action for the benefit of future generations and unknown others. In RACF, AMS requires value trade-offs and compromise on antimicrobial use in an environment that is heavily reliant on antimicrobial drugs to perform caring functions. In the context of aged care, AMS is a technical solution to a deeply relational and socio-structural problem and there is a risk that carers (workers, families) are morally burdened by system failures that are not addressed in AMS solutions.

摘要

在澳大利亚,老年护理机构(RACF)是抗生素高使用场所。老年护理机构中抗菌药物的滥用导致了抗菌药物耐药性(AMR)负担,这种负担会影响现在和未来的个人及更广泛的公众。老年护理机构中的抗菌药物管理(AMS)措施,例如要求确诊感染,旨在尽量减少抗生素的不当使用。我们与46位有父母在接受老年护理的参与者进行了对话小组讨论,以更好地了解家庭对老年护理机构中抗生素使用和护理的看法。参与者在考虑自己父母的护理时,努力权衡价值取舍,在想象中的群体和未来危害与已知的个人短期舒适之间进行权衡,并优先考虑后者。抗菌药物耐药性方面的分配正义依赖于为子孙后代和不特定他人的利益承担集体道德责任并采取行动。在老年护理机构中,抗菌药物管理要求在严重依赖抗菌药物来履行护理职能的环境中,在抗菌药物使用方面进行价值权衡和妥协。在老年护理的背景下,抗菌药物管理是解决一个深层次的人际关系和社会结构问题的技术方案,存在一种风险,即护理人员(工作人员、家庭)会因抗菌药物管理解决方案未解决的系统故障而承受道德负担。

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本文引用的文献

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A just transition for antimicrobial resistance: planning for an equitable and sustainable future with antimicrobial resistance.抗微生物药物耐药性的公正转型:规划抗微生物药物耐药性的公平与可持续未来。
Lancet. 2024 Jun 29;403(10446):2766-2767. doi: 10.1016/S0140-6736(23)01687-2. Epub 2023 Sep 8.
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Justifying the More Restrictive Alternative: Ethical Justifications for One Health AMR Policies Rely on Empirical Evidence.为更具限制性的方案辩护:“同一健康”抗菌药物耐药性政策的伦理依据依赖于经验证据。
Public Health Ethics. 2022 Nov 7;16(1):22-34. doi: 10.1093/phe/phac025. eCollection 2023 Apr.
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The dilemmas of antimicrobial stewardship in aged care: The perspectives of the family members of older Australians.老年护理中抗菌药物管理的困境:澳大利亚老年人的家庭成员的观点。
Geriatr Nurs. 2023 Mar-Apr;50:117-123. doi: 10.1016/j.gerinurse.2023.01.016. Epub 2023 Feb 10.
4
Dismantling antibiotic infrastructures in residential aged care: The invisible work of antimicrobial stewardship (AMS).拆除住宅老年护理抗生素基础设施:抗菌药物管理(AMS)的无形工作。
Soc Sci Med. 2022 Jul;305:115094. doi: 10.1016/j.socscimed.2022.115094. Epub 2022 May 31.
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Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene bla.移动遗传元件在碳青霉烯类耐药基因 bla 全球传播中的作用。
Nat Commun. 2022 Mar 3;13(1):1131. doi: 10.1038/s41467-022-28819-2.
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Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis.2019 年全球细菌对抗菌药物耐药性的负担:系统分析。
Lancet. 2022 Feb 12;399(10325):629-655. doi: 10.1016/S0140-6736(21)02724-0. Epub 2022 Jan 19.
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National Trends in Antibiotic Use in Australian Residential Aged Care Facilities, 2005-2016.澳大利亚养老机构抗生素使用的国家趋势,2005-2016 年。
Clin Infect Dis. 2021 Jun 15;72(12):2167-2174. doi: 10.1093/cid/ciaa436.
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Quick fix for care, productivity, hygiene and inequality: reframing the entrenched problem of antibiotic overuse.解决医疗、生产力、卫生和不平等问题的快速方法:重新审视抗生素过度使用这一顽固问题。
BMJ Glob Health. 2019 Aug 15;4(4):e001590. doi: 10.1136/bmjgh-2019-001590. eCollection 2019.
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Evaluating the risks of public health programs: Rational antibiotic use and antimicrobial resistance.评估公共卫生计划的风险:合理使用抗生素和抗微生物药物耐药性。
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