Defais M
Biochimie. 1985 Mar-Apr;67(3-4):357-60. doi: 10.1016/s0300-9084(85)80080-8.
The adaptive response appears in E. coli after exposure to low levels of alkylating agents. This system is under the positive control of the ada gene. At least two enzymes are induced during the response: 3-methyladenine DNA glycosylase II and O6-methylguanine DNA methyltransferase. The latter is also the product of the ada gene.
在暴露于低水平烷基化剂后,大肠杆菌中会出现适应性反应。该系统受ada基因的正调控。反应过程中至少诱导出两种酶:3-甲基腺嘌呤DNA糖基化酶II和O6-甲基鸟嘌呤DNA甲基转移酶。后者也是ada基因的产物。