Baker A R, Prytherch D R, Evans D H, Bell P R
Cardiovasc Res. 1985 Sep;19(9):559-66. doi: 10.1093/cvr/19.9.559.
Aorto-iliac stenoses were characterised in terms of pressure drop and flow velocity in a canine model and in patients with occlusive arterial disease. Pressure above and below the stenosis was measured intra-arterially and flow related measurements were made at rest and during reactive hyperaemia in the dog, and following papaverine administration in patients. The addition of flow velocity information to the pressure drop across a stenosis gave an increased separation of stenoses in the experimental animal and also in man.
在犬类模型和患有闭塞性动脉疾病的患者中,根据压降和流速对主-髂动脉狭窄进行了特征描述。在犬类中,通过动脉内测量狭窄部位上方和下方的压力,并在静息状态和反应性充血期间进行与血流相关的测量;在患者中,则在给予罂粟碱后进行测量。将流速信息添加到跨狭窄部位的压降中,在实验动物和人类中都增加了对狭窄的区分度。