Naguy, MBBch, MSc, MRCPsych (UK), Psychiatrist, Kuwait Centre for Mental Health (KCMH), Jamal Abdul-Nassir St, Shuwaikh, State of Kuwait.
Al-Khadhari, MBBch, FRCP(C), Professor of Psychiatry, Head of Psychiatric Department, Kuwait Faculty of Medicine, Kuwait.
Psychopharmacol Bull. 2024 Jul 8;54(3):100-102.
Here, authors report on an interesting case of an adolescent with a diagnosis of schizo-affective disorder, maintained on LAI paliperidone palmitate that developed an unusual dystonic reaction in form of anismus that masquerade as constipation and faecal impaction. To our knowledge, this is one of the earliest reports of antipsychotic-induced anismus notably in adolescent population. Clinicians should be mindful of unusual forms of dyskinesias that might be associated with high-potency antipsychotic use.
这里，作者报告了一个有趣的病例，一名被诊断为精神分裂情感障碍的青少年，使用 LAI 棕榈酸帕利哌酮维持治疗，出现了一种不寻常的张力障碍反应，表现为肛门痉挛，伪装为便秘和粪便嵌塞。据我们所知，这是最早报告的抗精神病药引起的肛门痉挛之一，特别是在青少年人群中。临床医生应该注意可能与使用高效价抗精神病药相关的不寻常形式的运动障碍。
