外源性福斯曼糖脂在细胞上的封端
Capping of exogenous Forssman glycolipid on cells.
作者信息
Stern P L, Bretscher M S
出版信息
J Cell Biol. 1979 Sep;82(3):829-33. doi: 10.1083/jcb.82.3.829.
Abstract
When motile cells are incubated with Forssman glycolipid, the antigen is incorporated into the cells' plasma membranes. If cross-linked by antibody, the patched glycolipids cap. This process is sensitive to those drugs that are known to inhibit capping of protein antigens. The results support a flow mechanism for capping.
摘要
当可运动细胞与福斯曼糖脂一起孵育时，抗原会掺入细胞膜中。如果通过抗体交联，这些聚集的糖脂会形成帽状结构。这一过程对那些已知能抑制蛋白质抗原形成帽状结构的药物敏感。这些结果支持了一种关于形成帽状结构的流动机制。
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