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铜-氧加合物：C-H活化表征与性质的新趋势

Copper-oxygen adducts: new trends in characterization and properties towards C-H activation.

作者信息

De Tovar Jonathan, Leblay Rébecca, Wang Yongxing, Wojcik Laurianne, Thibon-Pourret Aurore, Réglier Marius, Simaan A Jalila, Le Poul Nicolas, Belle Catherine

机构信息

Université Grenoble-Alpes, CNRS, Département de Chimie Moléculaire Grenoble France

Aix Marseille Univ, CNRS, Centrale Marseille, iSm2, Institut des Sciences Moléculaires de Marseille Marseille France

出版信息

Chem Sci. 2024 May 13;15(27):10308-10349. doi: 10.1039/d4sc01762e. eCollection 2024 Jul 10.

DOI:10.1039/d4sc01762e
PMID:38994420
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11234856/
Abstract

This review summarizes the latest discoveries in the field of C-H activation by copper monoxygenases and more particularly by their bioinspired systems. This work first describes the recent background on copper-containing enzymes along with additional interpretations about the nature of the active copper-oxygen intermediates. It then focuses on relevant examples of bioinorganic synthetic copper-oxygen intermediates according to their nuclearity (mono to polynuclear). This includes a detailed description of the spectroscopic features of these adducts as well as their reactivity towards the oxidation of recalcitrant C -H bonds. The last part is devoted to the significant expansion of heterogeneous catalytic systems based on copper-oxygen cores ( within zeolite frameworks).

摘要

本综述总结了单加氧铜酶领域，尤其是其仿生体系在C-H活化领域的最新发现。这项工作首先描述了含铜酶的近期研究背景，以及对活性铜-氧中间体性质的更多解释。然后根据其核数（单核到多核），重点介绍了生物无机合成铜-氧中间体的相关实例。这包括对这些加合物的光谱特征及其对顽固C-H键氧化反应活性的详细描述。最后一部分致力于基于铜-氧核（在沸石骨架内）的多相催化体系的显著扩展。

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