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[非吸入性麻醉药对血液循环调节反射机制作用的比较特征]

[Comparative characteristics of the effect of noninhalational narcotics on the reflex mechanisms of blood circulation regulation].

作者信息

Martiuk S A, Makatun V N, Tsyrlin V A

出版信息

Farmakol Toksikol. 1979 Jul-Aug;42(4):365-8.

PMID:38996
Abstract

It has been shown in experiments on cats with intact brain, as well as on decerebrated and spinal animals that chloralose, sombrevine and viadril exert no pronounced effect on initial electric activity in the renal nerve or baroreceptor inhibition of the neurogenous vascular tone, but inhibit vasomotor responses at stimulation of highly liminal afferent fibers of the cerebrospinal nerves. In animals with intact brain, sodium hydroxybutyrate inhibiting baroreceptor reflexes enhanced vasomotor reactions caused by activation of cutaneous and visceral nerves.

摘要

在对大脑完整的猫以及去大脑和脊髓动物进行的实验中发现,水合氯醛、索姆布瑞文和维阿德里尔对肾神经的初始电活动或神经源性血管张力的压力感受器抑制没有明显影响,但在刺激脑脊神经的高阈传入纤维时会抑制血管运动反应。在大脑完整的动物中,抑制压力感受器反射的羟基丁酸钠会增强由皮肤和内脏神经激活引起的血管运动反应。

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