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[抗高血压化合物对压力感受器反射的下丘脑调节作用]

[Effect of antihypertensive compounds on the hypothalamic regulation of baroreceptor reflexes].

作者信息

Tsyrlin V A, Ekimov E N

出版信息

Farmakol Toksikol. 1980 Jan-Feb;43(1):49-52.

PMID:7379990
Abstract

In experiments on cats the effect of neurotropic drugs on the baroreceptor reflexes changes produced by stimulation of the hypothalamus was investigated. It is shown that diazepam, pentobarbital and oxylidin decrease vasomotor responses under hypothalamic stimulation not only because of the depression of the descending activation of the spinal cord vasomotor neurones processes, but also as a result of suppression of the baroreceptor reflexes hypothalamic regulation. Clonidine and dopegyt had no influence on the baroreflexes hypothalamic regulation.

摘要

在对猫的实验中,研究了神经营养药物对下丘脑刺激所产生的压力感受器反射变化的影响。结果表明,地西泮、戊巴比妥和奥昔利定在下丘脑刺激下降低血管运动反应,不仅是因为脊髓血管运动神经元下行激活过程受到抑制,还由于压力感受器反射的下丘脑调节受到抑制。可乐定和多潘立酮对压力反射的下丘脑调节没有影响。

相似文献

1
[Effect of antihypertensive compounds on the hypothalamic regulation of baroreceptor reflexes].[抗高血压化合物对压力感受器反射的下丘脑调节作用]
Farmakol Toksikol. 1980 Jan-Feb;43(1):49-52.
2
[Effect of hypotensive agents on baroreceptor reflexes in waking animals].
Biull Eksp Biol Med. 1979 Feb;87(2):166-8.
3
[Hypothalamic modulation of baroreceptor inhibition of the electrical activity in the renal nerve].[下丘脑对压力感受器抑制肾神经电活动的调节作用]
Biull Eksp Biol Med. 1985 Dec;100(12):645-7.
4
[Baroreflex regulation of arterial pressure and regional blood flow during emotional stress].
Fiziol Zh SSSR Im I M Sechenova. 1976 Oct;62(10):1466-73.
5
[The effect of clofelin on the carotid sinus and cardiopulmonary baroreceptor reflexes in man].[氯非林对人体颈动脉窦和心肺压力感受器反射的影响]
Eksp Klin Farmakol. 1992 May-Jun;55(3):50-2.
6
Effects of alpha-adrenoceptor-stimulating drugs on baroreceptor reflexes in conscious cats.
Eur J Pharmacol. 1980 Oct 3;67(1):75-83. doi: 10.1016/0014-2999(80)90010-2.
7
[Comparative characteristics of the effect of noninhalational narcotics on the reflex mechanisms of blood circulation regulation].[非吸入性麻醉药对血液循环调节反射机制作用的比较特征]
Farmakol Toksikol. 1979 Jul-Aug;42(4):365-8.
8
The vasomotor component of the carotid sinus baroreceptor reflex in the cat during stimulation of the hypothalamic defence area.猫在刺激下丘脑防御区时颈动脉窦压力感受器反射的血管运动成分。
J Physiol. 1972 Oct;226(1):57-78. doi: 10.1113/jphysiol.1972.sp009973.
9
Effects of kainic acid applied to the ventral surface of the medulla oblongata on vasomotor tone, the baroreceptor reflex and hypothalamic autonomic responses.将海藻酸应用于延髓腹侧面后对血管运动张力、压力感受器反射及下丘脑自主反应的影响。
Brain Res. 1982 Apr 22;238(1):65-76. doi: 10.1016/0006-8993(82)90771-5.
10
[Assessment of the influence of pharmacologic substances on pressor vasomotor reflexes in anesthetized animals].
Farmakol Toksikol. 1977 May-Jun;40(3):317-22.

引用本文的文献

1
Possible mechanisms underlying the pressure responses evoked in conscious cats by emotional stress.清醒猫在情绪应激下诱发压力反应的潜在机制。
Pflugers Arch. 1983 Jul;398(2):81-7. doi: 10.1007/BF00581052.