Santifort Koen, Bellekom Sophie, Carrera Ines, Mandigers Paul
IVC Evidensia Referral Hospital Arnhem, 6825 MB Arnhem, The Netherlands.
IVC Evidensia Referral Hospital Hart van Brabant, 5144 AM Waalwijk, The Netherlands.
Animals (Basel). 2024 Jun 23;14(13):1859. doi: 10.3390/ani14131859.
The aim of Part II of this two-part study is to describe and analyze the association of various aspects and measurements related to the morphometry of the skull and craniocervical region to CM/SM status of Pomeranians, by means of computed tomography (CT) and magnetic resonance imaging (MRI).
Prospectively, Pomeranians were included that underwent both CT and MRI studies of the head and cervicothoracic vertebral column. For those cases where qualitative classifications differed between observers, the experienced observer re-evaluated the studies and decided on a final classification that was used for further analysis. For quantitative measurements, the means of the observers' measurements were used for analysis.
Among statistically significant differences in measurements, we found that dogs with SM had a significantly shorter clivus length based on both MRI ( = 0.01) and CT measurements ( = 0.01), and a significantly smaller caudal cranial fossa area based on both MRI ( = 0.02) and CT measurements ( = 0.02).
Significant morphometrical differences were identified between dogs with or without CM/SM. The findings in this study add to those already described in other breeds and provide further insight into factors that may play a role in the pathogenesis of CM/SM in Pomeranians.
在这项分为两部分的研究中，第二部分的目的是通过计算机断层扫描（CT）和磁共振成像（MRI），描述和分析与博美犬颅骨和颅颈区域形态测量相关的各个方面及测量值与CM/SM状态之间的关联。
前瞻性地纳入接受头部和颈胸椎MRI和CT检查的博美犬。对于观察者之间定性分类存在差异的病例，由经验丰富的观察者重新评估检查结果，并确定最终分类用于进一步分析。对于定量测量，采用观察者测量值的均值进行分析。
在测量的统计学显著差异中，我们发现，基于MRI（P = 0.01）和CT测量（P = 0.01），患有SM的犬斜坡长度显著较短；基于MRI（P = 0.02）和CT测量（P = 0.02），患有SM的犬颅后窝面积显著较小。
在患有或未患有CM/SM的犬之间发现了显著的形态测量差异。本研究结果补充了其他品种中已描述的内容，并进一步深入了解了可能在博美犬CM/SM发病机制中起作用的因素。
