Zangirolamo Amanda Fonseca, Souza Anne Kemmer, Yokomizo Deborah Nakayama, Miguel Ana Karolyne Alves, Costa Márcio Carvalho da, Alfieri Amauri Alcindo, Seneda Marcelo Marcondes
National Institute of Science and Technology for Dairy Production Chain (INCT-LEITE), Universidade Estadual de Londrina, Londrina 86057-970, PR, Brazil.
Laboratory of Animal Reproduction, Universidade Estadual de Londrina, Londrina 86057-970, PR, Brazil.
Animals (Basel). 2024 Jul 3;14(13):1971. doi: 10.3390/ani14131971.
The microbiota plays an important role in numerous physiological processes, pathogenesis, development, and metabolism in different animal species. In humans, several studies have demonstrated an association between the vaginal microbiota and fertility rates, and even success in assisted reproduction techniques. In the context of cattle reproduction, although few studies have addressed the microbiota in a healthy state (which is not associated with diseases that affect the reproductive tract of cows), changes in its composition also seem to influence fertility. This review aims to explain the importance of the reproductive microbiota in female bovines and what is available in the literature regarding its possible role in increasing fertility. What are the challenges involved in this process? Future perspectives on its use and manipulation as a selection or intervention tool. Will it be possible to one day extrapolate the findings to reality and apply them in the field? In short, understanding the role of the reproductive microbiota of female bovines can signal the prospect of increasing production, whether of milk or meat, from the same number of animals, as it can optimize reproductive efficiency and perhaps become an allied tool for the economic profitability and sustainability of livestock farming.
微生物群在不同动物物种的众多生理过程、发病机制、发育和新陈代谢中发挥着重要作用。在人类中，多项研究表明阴道微生物群与生育率之间存在关联，甚至与辅助生殖技术的成功率也有关联。在牛的繁殖方面，尽管很少有研究涉及健康状态下的微生物群（即与影响母牛生殖道的疾病无关的微生物群），但其组成的变化似乎也会影响生育能力。本综述旨在解释雌性牛生殖微生物群的重要性，以及文献中关于其在提高生育能力方面可能作用的相关内容。这个过程涉及哪些挑战？将其作为选择或干预工具进行使用和操纵的未来前景如何？有朝一日是否有可能将这些发现推广到实际应用并应用于该领域？简而言之，了解雌性牛生殖微生物群的作用可能预示着在相同数量的动物中提高牛奶或肉类产量的前景，因为它可以优化繁殖效率，并且可能成为畜牧业经济盈利能力和可持续性的辅助工具。
