Department of Biomedicine, Institute of Veterinary Sciences, University of Tiaret, Tiaret 14000, Algeria.
Department of Clinical Sciences, Ross University School of Veterinary Medicine, Basseterre 00265, Saint Kitts and Nevis.
Int J Mol Sci. 2024 Oct 10;25(20):10923. doi: 10.3390/ijms252010923.
This review paper delves into the intricate relationship between the genital microbiome and fertility outcomes in livestock, with a specific focus on cattle. Drawing upon insights derived from culture-independent metagenomics studies, the paper meticulously examines the composition and dynamics of the genital microbiome. Through advanced techniques such as high-throughput sequencing, the review illuminates the temporal shifts in microbial communities and their profound implications for reproductive health. The analysis underscores the association between dysbiosis-an imbalance in microbial communities-and the development of reproductive diseases, shedding light on the pivotal role of microbial gatekeepers in livestock fertility. Furthermore, the paper emphasizes the need for continued exploration of uncharted dimensions of the female reproductive microbiome to unlock new insights into its impact on fertility. By elucidating the complex interplay between microbial communities and reproductive health, this review underscores the importance of innovative strategies aimed at enhancing fertility and mitigating reproductive diseases in livestock populations.
这篇综述论文深入探讨了生殖道微生物组与家畜生育结果之间的复杂关系，特别关注牛。该论文借鉴了非培养宏基因组学研究的见解，细致研究了生殖道微生物组的组成和动态。通过高通量测序等先进技术，本综述揭示了微生物群落的时间变化及其对生殖健康的深远影响。分析强调了菌群失调（微生物群落失衡）与生殖疾病发展之间的关联，突显了微生物守门员在家畜生育中的关键作用。此外，该论文强调需要继续探索女性生殖道微生物组的未知维度，以深入了解其对生育的影响。通过阐明微生物群落与生殖健康之间的复杂相互作用，本综述强调了旨在提高家畜群体生育能力和减轻生殖疾病的创新策略的重要性。
