McCune R J, Bojanini J, Abodeely R A
J Am Dent Assoc. 1979 Oct;99(4):619-23. doi: 10.14219/jada.archive.1979.0344.
With use of the half-mouth technique, a pit and fissure sealant was applied to the permanent first molars of 200 children between 6 and 8 years of age in a community with fluoridated water in Colombia, South America. Complete retention of sealant at 12, 24, and 36 months after application was 91.6%, 88.9%, and 87.5%, respectively. Partial retention of sealant was 5.8%, 7.1%, and 8.5% at the same intervals. The incidence of caries in all sealant-treated teeth at 36 months was 8% vs 53% in untreated paired teeth. Of the 238 teeth that completely retained sealant, only one tooth had occlusal caries at 36 months. No statistically significant difference in complete retention between maxillary and mandibular molars was noticed at any examination. The study confirms that this cold-cured pit and fissure sealant is effective in protecting the occlusal surfaces of teeth against caries for at least three years.
在南美洲哥伦比亚一个有含氟水的社区，对200名6至8岁儿童的恒上第一磨牙采用半口技术应用窝沟封闭剂。封闭剂在应用后12个月、24个月和36个月时的完全保留率分别为91.6%、88.9%和87.5%。在相同时间段内，封闭剂的部分保留率分别为5.8%、7.1%和8.5%。36个月时，所有接受封闭剂治疗牙齿的龋病发生率为8%，而未治疗的配对牙齿为53%。在完全保留封闭剂的238颗牙齿中，36个月时只有一颗牙齿发生了咬合面龋。在任何一次检查中，上颌磨牙和下颌磨牙在完全保留率方面均未发现统计学上的显著差异。该研究证实，这种冷固化窝沟封闭剂在保护牙齿咬合面预防龋病方面至少三年有效。
