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[高分辨率实时超声检查在恶性黑色素瘤诊断中的进展]

[Diagnostic progress in malignant melanomas by high-resolution real-time sonography].

作者信息

Kraus W, Nake-Elias A, Schramm P

出版信息

Hautarzt. 1985 Jul;36(7):386-92.

PMID:3899995
Abstract

High-resolution real-time sonography enables visualization of the morphology of the cutis and subcutaneous layers. Evaluation of 19 malignant melanomas showed that tumors of a thickness of more than 0.6 mm can be seen sonographically. Malignant melanomas are revealed as nodules with very sparse internal echoes and sharp delineation, situated in the upper cutis. Infiltration of the subcutis can be shown reliably. The sonographically measured values of maximal tumor thickness show a good correlation with those determined postoperatively by histometry (r = 0.95). Regional metastases of melanomas and recurrencies are also revealed as sharply limited lesions with very few internal echoes. They can readily be separated from benign regressive nodules. Out of 237 examinations, the 181 evaluated ones showed a sonography sensitivity of 95% and a specificity of 99%. Therefore, an earlier diagnosis of regional metastases and recurrencies, as well as more precise indication for second operations during melanoma tumor follow-up can be made, and, in future, the decision for primary regional lymphonodectomy may be influenced. High-resolution sonography is thus a diagnostic imaging method which helps to evaluate preoperatively both malignant melanomas and their regional lymphatic areas.

摘要

高分辨率实时超声检查能够显示皮肤和皮下层的形态。对19例恶性黑色素瘤的评估显示,厚度超过0.6mm的肿瘤可通过超声检查看到。恶性黑色素瘤表现为位于皮肤浅层的结节,内部回声极少,边界清晰。皮下浸润能够可靠显示。超声测量的肿瘤最大厚度值与术后组织测量值具有良好的相关性(r = 0.95)。黑色素瘤的区域转移和复发同样表现为边界清晰、内部回声极少的病灶。它们很容易与良性退行性结节区分开来。在237次检查中,181次评估显示超声检查的敏感性为95%,特异性为99%。因此,可对区域转移和复发进行更早的诊断,以及在黑色素瘤肿瘤随访期间对二次手术进行更精确的指征判断,并且未来可能会影响原发性区域淋巴结切除术的决策。因此,高分辨率超声是一种诊断成像方法,有助于术前评估恶性黑色素瘤及其区域淋巴区域。

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