抗病毒药物研发。
Antiviral Drug Discovery.
机构信息
Department of Medicinal Chemistry, Key Laboratory of Chemical Biology, Ministry of Education, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
出版信息
Int J Mol Sci. 2024 Jul 6;25(13):7413. doi: 10.3390/ijms25137413.
Abstract
A vast and painful price has been paid in the battle against viruses in global health [...].
摘要
在全球卫生对抗病毒的战斗中，付出了巨大而痛苦的代价。
相似文献
1
Antiviral Drug Discovery.抗病毒药物研发。
Int J Mol Sci. 2024 Jul 6;25(13):7413. doi: 10.3390/ijms25137413.
2
Editorial overview: Engineering for viral resistance.编辑概述：抗病毒工程
Curr Opin Virol. 2015 Oct;14:v-vii. doi: 10.1016/j.coviro.2015.08.009. Epub 2015 Aug 28.
3
Application of modified antisense oligonucleotides and siRNAs as antiviral drugs.修饰的反义寡核苷酸和小干扰RNA作为抗病毒药物的应用。
Future Med Chem. 2015;7(13):1637-42. doi: 10.4155/fmc.15.114. Epub 2015 Sep 18.
4
Editorial overview: antivirals and resistance: advances and challenges ahead.社论综述：抗病毒药物与耐药性：未来的进展与挑战
Curr Opin Virol. 2014 Oct;8:iv-vii. doi: 10.1016/j.coviro.2014.08.002. Epub 2014 Aug 22.
5
A prospects tool in virus research: Analyzing the applications of organoids in virus studies.病毒研究中的一种前景工具：分析类器官在病毒研究中的应用。
Acta Trop. 2024 Jun;254:107182. doi: 10.1016/j.actatropica.2024.107182. Epub 2024 Mar 11.
6
Structural biology in antiviral drug discovery.抗病毒药物研发中的结构生物学
Curr Opin Pharmacol. 2016 Oct;30:116-130. doi: 10.1016/j.coph.2016.08.014. Epub 2016 Sep 6.
7
Nucleic acid-based drugs against emerging zoonotic viruses.针对新发人畜共患病毒的核酸类药物。
Future Med Chem. 2015;7(13):1709-19. doi: 10.4155/fmc.15.112. Epub 2015 Sep 24.
8
Drug targets in viral infections.病毒感染中的药物靶点。
Infect Disord Drug Targets. 2009 Apr;9(2):100. doi: 10.2174/187152609787847767.
9
Human viral diseases: what is next for antiviral drug discovery?人类病毒性疾病：抗病毒药物研发的下一步是什么？
Curr Opin Virol. 2012 Oct;2(5):572-9. doi: 10.1016/j.coviro.2012.07.004. Epub 2012 Jul 28.
10
The program of antiviral agents inhibits virus infection.抗病毒药物程序可抑制病毒感染。
Arch Microbiol. 2018 Aug;200(6):841-846. doi: 10.1007/s00203-018-1525-z. Epub 2018 May 30.
引用本文的文献
1
Piperazine-Substituted Pyranopyridines Exhibit Antiproliferative Activity and Act as Inhibitors of HBV Virion Production.哌嗪取代的吡喃并吡啶具有抗增殖活性，并可作为乙肝病毒颗粒产生的抑制剂。
Int J Mol Sci. 2025 Apr 23;26(9):3991. doi: 10.3390/ijms26093991.
本文引用的文献
1
Design and Synthesis of New GS-6207 Subtypes for Targeting HIV-1 Capsid Protein.设计并合成针对 HIV-1 衣壳蛋白的新型 GS-6207 亚型。
Int J Mol Sci. 2024 Mar 27;25(7):3734. doi: 10.3390/ijms25073734.
2
Baicalin Protects Broilers against Avian Coronavirus Infection via Regulating Respiratory Tract Microbiota and Amino Acid Metabolism.黄芩苷通过调节呼吸道微生物群和氨基酸代谢来保护肉鸡免受禽冠状病毒感染。
Int J Mol Sci. 2024 Feb 9;25(4):2109. doi: 10.3390/ijms25042109.
3
Assessing the Potential Contribution of In Silico Studies in Discovering Drug Candidates That Interact with Various SARS-CoV-2 Receptors.评估计算机模拟研究在发现与各种 SARS-CoV-2 受体相互作用的药物候选物方面的潜在贡献。
Int J Mol Sci. 2023 Oct 24;24(21):15518. doi: 10.3390/ijms242115518.
4
AI-Driven De Novo Design and Molecular Modeling for Discovery of Small-Molecule Compounds as Potential Drug Candidates Targeting SARS-CoV-2 Main Protease.人工智能驱动的从头设计和分子建模发现小分子化合物作为潜在的靶向 SARS-CoV-2 主蛋白酶的药物候选物。
Int J Mol Sci. 2023 Apr 29;24(9):8083. doi: 10.3390/ijms24098083.
5
Comparing the Effects of Rocaglates on Energy Metabolism and Immune Modulation on Cells of the Human Immune System.比较罗格列酮对人体免疫系统细胞能量代谢和免疫调节的影响。
Int J Mol Sci. 2023 Mar 20;24(6):5872. doi: 10.3390/ijms24065872.
6
Antiviral Effect of Ginsenosides rk1 against Influenza a Virus Infection by Targeting the Hemagglutinin 1-Mediated Virus Attachment.人参皂苷 rk1 通过靶向血凝素 1 介导的病毒附着抑制甲型流感病毒感染的抗病毒作用。
Int J Mol Sci. 2023 Mar 4;24(5):4967. doi: 10.3390/ijms24054967.
7
Covalently Targeted Highly Conserved Tyr318 to Improve the Drug Resistance Profiles of HIV-1 NNRTIs: A Proof-of-Concept Study.共价靶向高度保守的 HIV-1 NNRTIs 酪氨酸 318 以改善耐药性特征：概念验证研究。
Int J Mol Sci. 2023 Jan 7;24(2):1215. doi: 10.3390/ijms24021215.
8
Antiviral Approaches against Influenza Virus.抗流感病毒的策略。
Clin Microbiol Rev. 2023 Mar 23;36(1):e0004022. doi: 10.1128/cmr.00040-22. Epub 2023 Jan 16.
9
Influenza antivirals and their role in pandemic preparedness.流感抗病毒药物及其在大流行准备中的作用。
Antiviral Res. 2023 Feb;210:105499. doi: 10.1016/j.antiviral.2022.105499. Epub 2022 Dec 23.
10
Establishment and Cross-Protection Efficacy of a Recombinant Avian Gammacoronavirus Infectious Bronchitis Virus Harboring a Chimeric S1 Subunit.一种携带嵌合S1亚基的重组禽γ冠状病毒传染性支气管炎病毒的构建及其交叉保护效力
Front Microbiol. 2022 Jul 22;13:897560. doi: 10.3389/fmicb.2022.897560. eCollection 2022.
Zotero 插件