A comparative trial of the diagnostic quality of and tolerance for two concentrations of ioxaglate when used for phlebography.

We report a prospective, randomised, double blind study comparing the diagnostic quality of and tolerance for ascending phlebography in 100 patients using two different concentrations of ioxaglate, 320 mg/ml and 200 mg/ml. The immediate and delayed side effects were minimal in both groups and the difference between the two concentrations was not statistically significant. All the phlebograms were of diagnostic quality. We conclude that, with its lower osmolality, lower viscosity and lower cost, ioxaglate 200 mg/ml is a suitable medium for routine use in ascending phlebography of lower limbs.