A comparative trial of the diagnostic quality of and tolerance for two low concentration low osmolality contrast media for phlebography.

We report a prospective randomised double blind study comparing the diagnostic quality of and tolerance for ascending phlebography in 100 patients using two different low osmolality contrast media, ioxaglate and iohexol, at a concentration of 200 mg I/ml. The immediate and delayed side effects were minimal in both groups and the difference between the two media was not statistically significant. All the phlebograms were of diagnostic quality. We conclude that both ioxaglate and iohexol are suitable agents for leg phlebography in low concentrations.