Petkovic Ana, Menkovic Nemanja, Petrovic Olga, Bilbija Ilija, Nisevic Miodrag, Radovanovic Nikola N, Stanisavljevic Dejana, Putnik Svetozar, Maksimovic Ruzica, Ivanovic Branislava
Diagnostic Department of Center of Stereotaxic Radiosurgery, Clinic of Neurosurgery, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Cardiology Clinic, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Diagnostics (Basel). 2024 Jun 26;14(13):1355. doi: 10.3390/diagnostics14131355.
Infective endocarditis is a rare disease with an increasing incidence and an unaltered high mortality rate, despite medical development. Imaging plays an integrative part in the diagnosis of infective endocarditis, with echocardiography as the initial diagnostic test. Research data in the utility of cardiac computed tomography (CCT) in the diagnostic algorithm of IE are rising, which indicates its importance in detection of IE-related lesion along with the exclusion of coronary artery disease. The latest 2023 European Society of Cardiology Guidelines in the management of IE classified CCT as class of recommendation I and level of evidence B in detection of both valvular and paravalvular lesions in native and prosthetic valve endocarditis. This review article provides a comprehensive and contemporary review of the role of CCT in the diagnosis of IE, the optimization of acquisition protocols, the morphology characteristics of IE-related lesions, the published data of the diagnostic performance of CCT in comparison to echocardiography as the state-of-art method, as well as the limitations and future possibilities.
感染性心内膜炎是一种罕见疾病，尽管医学不断发展，但其发病率仍在上升，死亡率居高不下。影像学在感染性心内膜炎的诊断中发挥着综合作用，超声心动图是初始诊断检查方法。关于心脏计算机断层扫描（CCT）在感染性心内膜炎诊断算法中的应用研究数据不断增加，这表明其在检测感染性心内膜炎相关病变以及排除冠状动脉疾病方面的重要性。最新的2023年欧洲心脏病学会感染性心内膜炎管理指南将CCT在检测天然瓣膜和人工瓣膜心内膜炎的瓣膜及瓣周病变方面归类为推荐等级I和证据水平B。本文综述全面且与时俱进地阐述了CCT在感染性心内膜炎诊断中的作用、采集方案的优化、感染性心内膜炎相关病变的形态特征、与作为当前先进方法的超声心动图相比CCT诊断性能的已发表数据，以及其局限性和未来可能性。
