Andronic Mihaela, Scripcariu Dragoș-Viorel, Palaghia Mădălina Maria, Trofin Ana-Maria, Bejan Valentin, Scripcariu Viorel
First Surgical Clinic, Saint Spiridon Clinical Hospital, 700111 Iași, Romania.
Surgery Department, Regional Institute of Oncology Iași, 700483 Iasi, Romania.
Diagnostics (Basel). 2024 Jun 27;14(13):1367. doi: 10.3390/diagnostics14131367.
Due to its high aggressiveness and polyclonal tumor state, stomach cancer is considered a severe health problem. In this study, we analyzed Her2 and Ki67 in correlation with patient data for the possibility of prognostic factors. The study included 48 cases of gastric tumors that had been surgically treated in a period of five years. The percentage was statistically significant for intestinal-type adenocarcinomas located in the medio-gastric region ( = 0.05); in the diffuse subtype, there were no Her2 positive samples, and in the mixed subtype only one out of three samples was Her2 positive. Our results confirm the existing data, and we can conclude that this link can be considered a prognostic factor in the progression and treatment effectiveness.
由于其高侵袭性和多克隆肿瘤状态，胃癌被认为是一个严重的健康问题。在本研究中，我们分析了Her2和Ki67与患者数据的相关性，以探讨其作为预后因素的可能性。该研究纳入了在五年期间接受手术治疗的48例胃肿瘤病例。位于胃中部的肠型腺癌的百分比具有统计学意义（P = 0.05）；在弥漫亚型中，没有Her2阳性样本，在混合亚型中，三个样本中只有一个Her2阳性。我们的结果证实了现有数据，并且我们可以得出结论，这种关联可被视为进展和治疗效果的预后因素。
