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阴道松弛与阴道分娩次数及分娩方式有关吗?

Is Vaginal Laxity Associated with Vaginal Parity and Mode of Delivery?

作者信息

Mustafa-Mikhail Susana, Gillor Moshe, Francis Yara Nakhleh, Dietz Hans Peter

机构信息

Sydney Medical School Nepean, University of Sydney, Sydney, NSW, Australia.

Galilee Medical Center, Naharyia, Affiliated to The Azrieli Faculty of Medicine of Bar-Ilan University, Yermiaho Halperin 2, Haifa, Safed, Israel.

出版信息

Int Urogynecol J. 2024 Dec;35(12):2323-2328. doi: 10.1007/s00192-024-05849-6. Epub 2024 Jul 13.

DOI:10.1007/s00192-024-05849-6
PMID:39002044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11732910/
Abstract

INTRODUCTION AND HYPOTHESIS

Vaginal laxity (VL) is a common symptom of pelvic floor dysfunction. Although VL has become a frequent topic for research in the last decade, its pathogenesis is still not well understood. The objective was to determine whether vaginal parity or mode of delivery is associated with vaginal laxity.

METHODS

This was a retrospective observational study involving women seen in a tertiary urogynecology clinic between May 2016 and November 2018 with symptoms of pelvic floor dysfunction. Patients underwent a standardized interview, clinical examination (POP-Q), and four-dimensional (4D) pelvic floor ultrasound (PFUS). Data regarding vaginal parity and the mode of delivery were based on patient-reported information. Archived 4D-PFUS volumes were analyzed offline to evaluate levator hiatal area on Valsalva.

RESULTS

Data from 1,051 patients were analyzed. VL was reported by 236 women (23%) who were younger on average (mean age 54 vs 59 years, p < 0.001) and less likely to be menopausal (530 out of 815 [65.0%] vs.129 out of 236 [54.7%]), p = 0.004]. Symptoms of prolapse were much more common in the VL group (214 out of 236 [91%] vs 316 out of 815 [39%], p =  < 0.001) and on imaging mean levator hiatal area (HA) on Valsalva was larger (31 vs 26 cm, p = 0.01). Vaginal parity was associated with VL symptoms (235 out of 236 [99%] vs 767 out of 815 [94%], p = 0.008), but neither VL prevalence nor bother increased with higher parity. Women who delivered vaginally were three times more likely to complain of VL than those who delivered only by cesarean section.

CONCLUSIONS

Vaginal laxity was found to be more prevalent in vaginally parous women. This effect seems to be largely attributable to the first delivery. Instrumental delivery was not shown to increase association with VL compared with normal vaginal delivery.

摘要

引言与假设

阴道松弛(VL)是盆底功能障碍的常见症状。尽管在过去十年中,阴道松弛已成为一个频繁的研究课题,但其发病机制仍未得到充分了解。目的是确定阴道分娩次数或分娩方式是否与阴道松弛有关。

方法

这是一项回顾性观察研究,涉及2016年5月至2018年11月在三级泌尿妇科诊所就诊的有盆底功能障碍症状的女性。患者接受了标准化访谈、临床检查(盆腔器官脱垂定量分期系统[POP-Q])和四维(4D)盆底超声(PFUS)检查。关于阴道分娩次数和分娩方式的数据基于患者报告的信息。对存档的4D-PFUS容积进行离线分析,以评估用力屏气时提肛肌裂孔面积。

结果

分析了1051例患者的数据。236名女性(23%)报告有阴道松弛,她们平均年龄更小(平均年龄54岁对59岁,p<0.001),绝经的可能性更低(815例中有530例[65.0%]对236例中有129例[54.7%]),p=0.004]。脱垂症状在阴道松弛组中更为常见(236例中有214例[91%]对815例中有316例[39%],p<0.001),并且在影像学上,用力屏气时平均提肛肌裂孔面积(HA)更大(31平方厘米对26平方厘米,p=0.01)。阴道分娩次数与阴道松弛症状有关(236例中有235例[99%]对815例中有767例[94%],p=0.008),但阴道松弛的患病率和困扰程度均不会随着分娩次数的增加而升高。经阴道分娩的女性抱怨阴道松弛的可能性是仅通过剖宫产分娩的女性的三倍。

结论

发现阴道松弛在经阴道分娩的女性中更为普遍。这种影响似乎很大程度上归因于首次分娩。与正常阴道分娩相比,器械助产并未显示出与阴道松弛的关联增加。