Service de chirurgie maxillofaciale et chirurgie plastique, Hôpital Necker Enfants malades, 75015 Paris, France; CRMR MAFACE, Hôpital Necker Enfants malades, 75015 Paris, France.
Laboratoire de Phonétique et Phonologie UMR 7018- CNRS/Sorbonne Nouvelle.
J Stomatol Oral Maxillofac Surg. 2024 Sep;125(5S1):101968. doi: 10.1016/j.jormas.2024.101968. Epub 2024 Jul 11.
The objective of this study is to utilize the Nasometer to objectively assess velopharyngeal competence, specifically through the quantification of nasalance. Initial calibration of the nasometer was conducted on American adults. The objective of this study was to validate the use of the nasometer for the objective diagnosis of velopharyngeal insufficiency (VPI) in French children born with a total cleft lip and palate and to select relevant verbal stimuli for clinical practice.
The nasalance scores of 42 children aged 8 to 10 years old, born with a cleft lip and palate, were collected and compared with 50 control children. The scores were then analyzed in relation to 31 verbal stimuli from the French corpus created for this study (sentences and syllables). The most relevant threshold values were determined by receiver operating characteristic curves, which exhibited the highest sensitivity and specificity.
The results demonstrated statistically significant differences (p < 0.05) in the mean nasalance scores of the control and cleft groups for all verbal stimuli containing oral phonemes. Threshold values with good diagnostic accuracy were defined, and 15 verbal stimuli were selected for use in clinical practice.
The nasalance threshold values defined in this study can be utilized for the objective diagnosis of velopharyngeal insufficiency (VPI) and the subsequent monitoring of French children aged 8 to 10 years old, born with a cleft lip and palate.
本研究旨在利用 Nasometer 客观评估腭咽功能，特别是通过鼻共鸣值的量化。Nasometer 的初始校准是在美国成年人中进行的。本研究的目的是验证 Nasometer 用于客观诊断法国完全腭裂儿童的腭咽闭合不全（VPI）的有效性，并选择相关的言语刺激用于临床实践。
收集了 42 名 8 至 10 岁的腭裂儿童的鼻共鸣值，并与 50 名对照组儿童进行了比较。然后，根据本研究创建的法语语料库中的 31 个言语刺激（句子和音节）对分数进行了分析。通过接收者操作特征曲线确定了最相关的阈值，该曲线表现出最高的敏感性和特异性。
对于所有包含口腔音的言语刺激，对照组和腭裂组的平均鼻共鸣值均存在统计学显著差异（p<0.05）。定义了具有良好诊断准确性的阈值，并选择了 15 个言语刺激用于临床实践。
本研究中定义的鼻共鸣阈值可用于客观诊断腭咽闭合不全（VPI），并随后监测 8 至 10 岁的法国腭裂儿童。
