Animal Bioscience and Biotechnology Laboratory, United States Department of Agriculture, Agricultural Research Service, Beltsville, MD 20705, USA.
National Agricultural Library, United States Department of Agriculture, Agricultural Research Service, Beltsville, MD 20705, USA.
Poult Sci. 2024 Sep;103(9):103987. doi: 10.1016/j.psj.2024.103987. Epub 2024 Jun 20.
The need to develop novel alternatives to antibiotics gained prominence following the ban on sub-therapeutic antibiotic applications for livestock growth enhancement. This prohibition led to a surge in research papers exploring potential alternatives to antibiotics to promote growth and health in poultry. As a result, it has become imperative to synthesize information regarding research accomplishments and publication patterns in antibiotic alternatives, to assess research gaps and aid regulatory, funding, and research entities in making informed decisions. Consequently, our study aims to systematically analyze and comprehend the research and publication trends related to growth-promoting antibiotic alternatives in poultry. We identified all publications during the search period from 2009 to 2022, utilizing various bibliometric analysis datasets from Scopus, Web of Science/InCites, and Dimensions. The Rayyan web application was employed for manual deduplicating, labeling, and screening the relevant publications. From an initial pool of 2038 publications, we screened and categorized 816 based on factors such as alternative antibiotic categories, publication years, countries, species, journals, and institutes. Our findings reveal that the most prevalent publications are centered around probiotic (30.51%) and phytogenic (24.02%). Notably, the United States leads publication output, followed by China and Egypt. Among poultry species, broilers emerge as the most extensively studied category, followed by layer chickens. Universities emerge as the foremost contributors to antibiotic alternative research, while government institutes and industry occupy the second and third positions, respectively. Upon scrutinizing the journals responsible for the highest publication count and most cited papers, it became evident that the journal "Poultry Science" leads with the highest percentage (13.51%) and the most highly cited publications, accounting for five out of eleven highly cited articles. This comprehensive review outlines research trends concerning diverse antibiotic alternatives, taking into account poultry species and geographical distribution. The future trajectory in this domain is projected to encompass a blend of various antibiotic alternatives that could be administered as a single product and/or the innovative use of novel antibiotic alternatives.
随着禁止在畜牧业中使用低于治疗剂量的抗生素来促进生长，开发新型抗生素替代品的需求变得尤为重要。这一禁令促使大量研究论文涌现，旨在探索抗生素替代品，以促进家禽的生长和健康。因此，有必要综合评估抗生素替代品研究成果和发表模式，了解研究空白，为监管、资助和研究实体提供决策依据。因此，我们的研究旨在系统分析和理解家禽中促生长抗生素替代品的研究和发表趋势。我们利用 Scopus、Web of Science/InCites 和 Dimensions 中的各种文献计量分析数据集，确定了 2009 年至 2022 年搜索期间的所有出版物。我们使用 Rayyan 网络应用程序进行手动去重、标记和筛选相关出版物。在最初的 2038 篇出版物中，我们根据替代抗生素类别、发表年份、国家、物种、期刊和机构等因素筛选和分类了 816 篇。我们的研究结果表明，最常见的出版物集中在益生菌（30.51%）和植物源（24.02%）上。值得注意的是，美国在出版物数量上处于领先地位，其次是中国和埃及。在家禽种类中，肉鸡是研究最多的类别，其次是蛋鸡。大学是抗生素替代品研究的主要贡献者，而政府研究所和工业界分别位居第二和第三位。通过研究发表数量最多和被引频次最高的期刊，我们发现《家禽科学》期刊以 13.51%的最高百分比和五篇被引频次最高的文章（占被引频次最高的 11 篇文章中的 5 篇）位居榜首。本综述概述了不同抗生素替代品的研究趋势，同时考虑了家禽种类和地理分布。该领域的未来趋势预计将涵盖多种抗生素替代品的混合使用，这些替代品可以作为单一产品使用，也可以创新使用新型抗生素替代品。
