School of Materials Science and Engineering, Dalian University of Technology, Dalian 116024, China.
School of Materials Science and Engineering, Dalian University of Technology, Dalian 116024, China.
J Biomech. 2024 Jul;172:112227. doi: 10.1016/j.jbiomech.2024.112227. Epub 2024 Jul 11.
Considering the high strength and excellent biocompatibility of low-nickel stainless steel, this paper focused on optimizing the design of a vascular stent made from this material using finite element analysis (FEA) combined with the response surface methodology (RSM). The aim is to achieve the desired compressive resistance for the stent while maintaining a thin stent wall thickness. The parameters of the stent's support unit width (H), strut width (W), and thickness (T) were selected as input parameters, while the output parameters obtained from FEA included the compressive load, the equivalent plastic strain (PEEQ), axial shortening rate, radial recoil rate, and metal coverage rate. The mathematical models of input parameters and output parameters were established by using the Box Behnken design (BBD) of RSM. The model equations were solved under constrained conditions, and the optimal structural parameters, namely H, W, and T, were finally determined as 0.770 mm, 0.100 mm, and 0.075 mm respectively. In this situation, the compression load of the stent reached the target value of 0.38 N/mm; the PEEQ resulting from the stent expansion was small; the axial shortening, radial recoil, and metal coverage index were all minimized within the required range.
考虑到低镍不锈钢的高强度和优异的生物相容性，本文专注于使用有限元分析（FEA）结合响应面法（RSM）优化这种材料制成的血管支架的设计。目的是在保持支架壁较薄的情况下，为支架实现所需的抗压能力。支架的支撑单元宽度（H）、支柱宽度（W）和厚度（T）的参数被选为输入参数，而从 FEA 获得的输出参数包括压缩负载、等效塑性应变（PEEQ）、轴向缩短率、径向回弹率和金属覆盖率。通过 RSM 的 Box Behnken 设计（BBD）建立输入参数和输出参数的数学模型。在约束条件下求解模型方程，最终确定最佳结构参数 H、W 和 T 分别为 0.770mm、0.100mm 和 0.075mm。在这种情况下，支架的压缩负载达到 0.38N/mm 的目标值；支架扩张产生的 PEEQ 较小；轴向缩短、径向回弹和金属覆盖率指数都在所需范围内最小化。
