非毒力质粒编码抗原诱导的对耶尔森氏菌感染的保护作用。
Protection against Yersinia infection induced by non-virulence-plasmid-encoded antigens.
作者信息
Simonet M, Berche P, Mazigh D, Veron M
出版信息
J Med Microbiol. 1985 Oct;20(2):225-31. doi: 10.1099/00222615-20-2-225.
PMID:3900406
Abstract
Specific immunity against Yersinia was induced by plasmid-encoded antigens not associated with virulence. Mice were immunised with viable bacteria from a virulence-plasmid-cured strain of Y. pseudotuberculosis. This antigenic stimulation generated specific protection against virulence-plasmid-harbouring strains of Y. pseudotuberculosis and Y. pestis, demonstrating that protection can be generated by organisms lacking plasmid-encoded virulence antigens.
摘要
由与毒力无关的质粒编码抗原诱导产生针对耶尔森菌的特异性免疫。用来自无毒力质粒的假结核耶尔森菌菌株的活细菌免疫小鼠。这种抗原刺激产生了针对携带毒力质粒的假结核耶尔森菌和鼠疫耶尔森菌菌株的特异性保护，表明缺乏质粒编码毒力抗原的生物体也能产生保护作用。
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