Stav Michael Yohay, Fein Shai, Matatov Yuri, Hoffman Dana, Heesen Philip, Binyamin Yair, Iluz-Freundlich Daniel, Eidelman Leonid, Orbach-Zinger Sharon
Department of Anesthesia, Rabin Medical Center Beilinson Hospital, Petah Tikva, Central, Israel
Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Reg Anesth Pain Med. 2024 Jul 14. doi: 10.1136/rapm-2024-105388.
Intraoperative pain during cesarean delivery with or without conversion to general anesthesia has been shown to negatively impact maternal and perinatal morbidity. Efforts to reduce these adverse events are a recent focus of obstetric anesthesia care. We aimed to assess rates of and risk factors for conversion to general anesthesia and intraoperative pain during intrapartum cesarean delivery with an indwelling epidural catheter in our academic center.
In this retrospective cohort study, all women undergoing cesarean delivery with an indwelling epidural catheter between January 2017 and June 2022 were included. Labor epidural analgesia was provided according to a standardized protocol, and conversion to epidural anesthesia was achieved in the operating room before surgery. We determined the conversion rate to general anesthesia and associated risk factors. Second, we examined the rate of administration of analgesics/sedatives and related risk factors in cesarean cases that were not converted to general anesthesia.
Among the 1192 women undergoing intrapartum cesarean delivery with epidural anesthesia, there were 97 cases with conversion to general anesthesia (8.1%), of which 87 (89.7%) were due to a failed epidural. Higher age, higher weight, and higher gestational age were associated with decreased odds of conversion to general anesthesia. Higher gravidity and longer surgical time were associated with increased odds. An emergent indication was not associated with conversion to general anesthesia. Intravenous analgesic/sedative supplementation occurred in 141 cases (12.9%). Higher age was associated with decreased odds of supplementation, and longer surgical time was associated with increased odds.
In our tertiary academic center, the rate of intraoperative conversion to general anesthesia and administration of analgesic/sedative medication among women undergoing intrapartum cesarean delivery with epidural anesthesia was relatively high. Emergency cesarean delivery was not associated with either of the above endpoints.
剖宫产术中无论是否转为全身麻醉,术中疼痛均已显示会对孕产妇和围产儿发病率产生负面影响。减少这些不良事件的努力是产科麻醉护理最近关注的焦点。我们旨在评估在我们学术中心,产时剖宫产留置硬膜外导管时转为全身麻醉的发生率及危险因素,以及术中疼痛情况。
在这项回顾性队列研究中,纳入了2017年1月至2022年6月期间所有接受剖宫产且留置硬膜外导管的妇女。根据标准化方案提供分娩期硬膜外镇痛,并在手术前在手术室实现硬膜外麻醉转换。我们确定了转为全身麻醉的发生率及相关危险因素。其次,我们检查了未转为全身麻醉的剖宫产病例中镇痛剂/镇静剂的给药率及相关危险因素。
在1192例接受硬膜外麻醉的产时剖宫产妇女中,有97例转为全身麻醉(8.1%),其中87例(89.7%)是由于硬膜外麻醉失败。年龄较大、体重较高和孕周较大与转为全身麻醉的几率降低相关。产次较高和手术时间较长与几率增加相关。急诊指征与转为全身麻醉无关。141例(12.9%)进行了静脉镇痛/镇静补充。年龄较大与补充几率降低相关,手术时间较长与几率增加相关。
在我们的三级学术中心,产时剖宫产接受硬膜外麻醉的妇女术中转为全身麻醉以及使用镇痛/镇静药物的发生率相对较高。急诊剖宫产与上述任何一个终点均无关。