Oral and Maxillofacial Radiology, Umeå University Hospital, Umeå, Sweden.
Oral and Maxillofacial Radiology, Department of Odontology, Umeå University, Umeå, Sweden.
BMC Oral Health. 2024 Jul 14;24(1):792. doi: 10.1186/s12903-024-04543-9.
Magnetic resonance imaging (MRI) of the brain is frequently performed on patients with neurofibromatosis type 1 (NF1), to detect and follow-up intracranial findings. In addition, NF1-related pathologies can appear in the jaws. This case study investigates if it is advantageous to assess the depicted parts of the jaws in the imaging of NF1 patients with intracranial findings, thereby detecting jaw pathologies in their initial stages.
We report on the 3-year management with clinical and radiological follow-ups of a central giant cell granuloma and a neurofibroma in the mandible of a patient with NF1 who underwent examinations with brain MRIs. A review of the mandible in the patient's MRIs disclosed lesions with clear differences in progression rates.
NF1-related jaw pathologies may be detected in the early stages if the depicted parts of the jaws are included in the assessment of the imaging of NF1 patients with intracranial findings. This could impact the treatment of eventual pathologies before lesion progression and further damage to the vicinity.
磁共振成像（MRI）常用于神经纤维瘤病 1 型（NF1）患者，以检测和随访颅内病变。此外，NF1 相关病变也可能出现在颌骨中。本病例研究旨在探讨在有颅内病变的 NF1 患者的影像学检查中评估颌骨的相关部位是否有助于在早期发现颌骨病变。
我们报告了一例 NF1 患者，其下颌中存在中央性巨细胞瘤和神经纤维瘤，通过脑部 MRI 检查进行了 3 年的临床和影像学随访。对患者 MRI 中下颌骨的回顾显示，病变的进展速度有明显差异。
如果在评估有颅内病变的 NF1 患者的影像学检查时包括颌骨的相关部位，则可能在早期发现 NF1 相关的颌骨病变。这可能会影响对潜在病变的治疗，避免病变进展和周围组织进一步受损。
