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1型神经纤维瘤病患者全景片中,下颌骨体部非牙源性骨内透射性病变是罕见表现。

Non-odontogenic Intraosseous Radiolucent Lesions of the Mandibular Body Are Rare Findings on Panoramic Views of Patients With Neurofibromatosis Type 1.

作者信息

Friedrich Reinhard E, Scheuer Hannah T

机构信息

Department of Oral and Craniomaxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany

Neurofibromatosis Laboratory Hamburg, Hamburg, Germany.

出版信息

Anticancer Res. 2019 Apr;39(4):1971-1985. doi: 10.21873/anticanres.13308.

Abstract

BACKGROUND/AIM: The purpose of the study was to investigate whether non-odontogenic intraosseous translucent lesions of mandibular body are depicted on radiographs of patients with neurofibromatosis type 1 (NF1).

MATERIALS AND METHODS

The panoramic radiographs of 179 NF1 patients were analysed for translucent lesions of the mandibular body that were of intraosseous, non-odontogenic origin. The results were compared to findings obtained in panoramic radiographs of age- and sex-matched controls.

RESULTS

Only three patients showed intraosseous translucent lesions. These were always unilocular findings. There were no statistically significant differences between the groups (p=0.248).

CONCLUSION

Intraosseous neurofibroma of the jaw is a very rare finding in NF1 patients compared to oral neurofibromas. Accurate and exact diagnosis should be made in the case of such findings because malignant tumours in the jaw area can arise in rare cases in NF1 patients. Plain radiology findings cannot clearly indicate the type and biology of the lesion.

摘要

背景/目的:本研究旨在调查1型神经纤维瘤病(NF1)患者的下颌骨非牙源性骨内透光性病变在X线片上是否有显示。

材料与方法

分析179例NF1患者的全景X线片,以查找下颌骨骨内非牙源性起源的透光性病变。将结果与年龄和性别匹配的对照组全景X线片的检查结果进行比较。

结果

仅3例患者显示骨内透光性病变。这些病变均为单房性。两组之间无统计学显著差异(p = 0.248)。

结论

与口腔神经纤维瘤相比,颌骨骨内神经纤维瘤在NF1患者中是非常罕见的发现。对于此类发现应进行准确诊断,因为NF1患者颌骨区域在罕见情况下可能会出现恶性肿瘤。普通放射学检查结果不能明确显示病变的类型和生物学特性。

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