Department of Industrial Management, National Taiwan University of Science and Technology, Taipei, Taiwan.
Geriatr Gerontol Int. 2024 Aug;24(8):766-772. doi: 10.1111/ggi.14925. Epub 2024 Jul 14.
Chronic diseases are influential components of stroke, one of the dominant reasons for dementia and premature mortality. Environmental risks are risk factors for transitioning from stroke to dementia. This study addresses the transition behaviors in stroke and dementia development associated with chronic diseases and environmental risks.
This study is an integrated survey of medical and environmental informatics concerning stroke patients' quality of life. A total of 10 627 stroke patients diagnosed in Taiwan were surveyed in this study. A covariate model and subgroup analysis were used to evaluate the influence of chronic diseases and environmental risk factors (i.e., divorce rate, unemployment rate, solitariness rate, temperature, and air pollution rate) on stroke and the corresponding dementia transition behaviors.
This study constructed a total of 98 covariate analysis models, consisting of 14 transition types [10 transitions from chronic diseases to stroke (5 metabolic risk states × 2 stroke states) and 4 transitions from stroke to dementia (2 stroke states × 2 dementia states)] by 7 covariates (i.e., sex, age, divorce rate, unemployment rate, temperature, air pollution, and solitariness rate). Among the 98 transitions, 26 were statistically significant.
Sex, age, divorce rate, unemployment rate, temperature, and air pollution rate exerted a partially significant influence on the transition from chronic diseases to stroke. Sex, age, unemployment rate, and temperature partially influenced the transition from stroke to dementia. This study also considered high-risk sub-populations of stroke patients, particularly males aged 65 years and below. Geriatr Gerontol Int 2024; 24: 766-772.
慢性病是中风的重要组成部分，也是痴呆和过早死亡的主要原因之一。环境风险是从中风转变为痴呆的风险因素。本研究探讨了与慢性病和环境风险相关的中风和痴呆发展的转变行为。
本研究是对与中风患者生活质量相关的医学和环境信息学的综合调查。本研究共调查了台湾 10627 名中风患者。使用协变量模型和亚组分析评估慢性病和环境风险因素（即离婚率、失业率、孤独率、温度和空气污染率）对中风及其相应痴呆转变行为的影响。
本研究共构建了 98 个协变量分析模型，包括 14 种转变类型[10 种由慢性病向中风的转变（5 种代谢风险状态×2 种中风状态）和 4 种由中风向痴呆的转变（2 种中风状态×2 种痴呆状态）]，由 7 个协变量（即性别、年龄、离婚率、失业率、温度、空气污染和孤独率）组成。在这 98 种转变中，有 26 种具有统计学意义。
性别、年龄、离婚率、失业率、温度和空气污染率对慢性病向中风的转变有一定影响。性别、年龄、失业率和温度对中风向痴呆的转变有一定影响。本研究还考虑了中风患者的高危亚人群，特别是 65 岁及以下的男性。老年医学与老年病学国际 2024; 24: 766-772.
