Savel'ev V Iu, Malyshev Iu M, Novikov I D, Korolev S V
Kardiologiia. 1985 Jun;25(6):88-92.
The authors present a mathematical model for determining the separated effective renal blood flow (ERB) and a computer program which was used to determine separate parameters of the ERB in 56 patients including 35 with a unilateral lesion of the kidneys (20 patients with renovascular hypertension and 15 with unilateral pyelonephritis) and 21 patients with symmetrical renal damage (12 patients with chronic diffuse glomerulonephritis and 9 with essential hypertension). The patients with a unilateral renal lesion exhibited a significant decrease in the ERB parameters on the affected side whilst the patients with the symmetrical damage showed no significant differences in the ERB values. Following the surgical correction of the stenosing renal artery, the patients with renovascular hypertension displayed in the presence of a pronounced hypotensive effect a redistribution of the ERB with its increase on the side of the interference. A similar although less evident tendency toward the predominant increase in the ERB on the affected side was also observed in the patients with unilateral pyelonephritis. The patients with the symmetrical damage to the kidneys presented no redistribution of the ERB after the treatment.
作者提出了一种用于确定分离的有效肾血流量（ERB）的数学模型以及一个计算机程序，该程序用于确定56例患者的ERB单独参数，其中包括35例单侧肾脏病变患者（20例肾血管性高血压患者和15例单侧肾盂肾炎患者）和21例双侧肾脏损害患者（12例慢性弥漫性肾小球肾炎患者和9例原发性高血压患者）。单侧肾脏病变患者患侧的ERB参数显著降低，而双侧损害患者的ERB值无显著差异。在对狭窄的肾动脉进行手术矫正后，肾血管性高血压患者在出现明显降压效果的情况下，ERB出现重新分布，干预侧的ERB增加。在单侧肾盂肾炎患者中也观察到类似但不太明显的倾向，即患侧ERB主要增加。双侧肾脏损害患者治疗后未出现ERB重新分布。
