A comparison of premeal subcutaneous insulin infusion and injection in type I diabetic patients under continuous basal subcutaneous insulin delivery.

Blood glucose control under continuous subcutaneous insulin infusion (CSII) was assessed in five type I diabetic patients by measurement of mean blood glucose and M-values. These results were compared with the data obtained from treatment with constant basal subcutaneous insulin delivery supplemented by injection of regular insulin before meals into changing sites of the anterior abdominal wall. CSII treatment gave significantly (P less than 0.05) better results. It might be assumed that this is due to the more reliable insulin absorption from an unchanged site.