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[持续皮下胰岛素输注可使I型糖尿病患者血糖正常,尽管饮食控制有所放松]

[Continuous subcutaneous insulin infusion brings about normal blood sugar in type I diabetes mellitus despite relaxing of diet instructions].

作者信息

Sonnenberg G E, Chantelau E, Altenähr H, Berger M, Berchtold P

出版信息

Schweiz Med Wochenschr. 1982 Jan 16;112(3):83-5.

PMID:7036337
Abstract

In 6 normal weight juvenile diabetic patients treated with continuous subcutaneous insulin infusion (CSII) we have investigated whether the restrictive management of the diabetes diet could be relaxed. On 2-3 days of a 4 week period the patients ate a) a conventional diabetes diet consisting of 3 main meals and in-between snacks of a prescribed carbohydrate content or b) a liberal diabetes diet in which the patients could choose the number of meals and carbohydrate contents. With both diets, mean blood glucose levels during the day were in normal range (96 +/- 3 and 101 +/- mg/dl, mean +/- SEM). On the liberal diet meal frequency and carbohydrate intake per day were significantly lower, the carbohydrate content per meal significantly larger when compared with the conventional diabetes diet. There was not difference in insulin requirements per day (basal rate plus premeal dosage). All the patients preferred the liberal diet. CSII allowed juvenile diabetic patients a more liberal management of their diabetes diet without negative effects on blood glucose control. Hence CSII improved the quality of life in these patients.

摘要

在6名接受持续皮下胰岛素输注(CSII)治疗的正常体重青少年糖尿病患者中,我们研究了糖尿病饮食的限制性管理是否可以放宽。在为期4周的2至3天里,患者分别食用:a)传统糖尿病饮食,包括3顿主餐以及规定碳水化合物含量的中间零食;b)自由糖尿病饮食,患者可以选择餐数和碳水化合物含量。两种饮食方式下,白天的平均血糖水平均在正常范围内(分别为96±3和101±mg/dl,均值±标准误)。与传统糖尿病饮食相比,自由饮食时每日餐次频率和碳水化合物摄入量显著更低,每餐碳水化合物含量显著更高。每日胰岛素需求量(基础率加餐时剂量)没有差异。所有患者都更喜欢自由饮食。CSII使青少年糖尿病患者能够更自由地管理其糖尿病饮食,而对血糖控制没有负面影响。因此,CSII改善了这些患者的生活质量。

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