Foulger Landon, Simmons Kelly, Schiano Michael, Bush Stephen
Gynecol. Oncol., Department of Obstetrics and Gynecology, Charleston Area Medical Center, Charleston, WV, United States.
Gynecol Oncol Rep. 2024 Jun 13;54:101435. doi: 10.1016/j.gore.2024.101435. eCollection 2024 Aug.
Vulvar cancer accounts for 0.3 % of new cancer cases within the Unites States. Metastatic vulvar cancer with disease beyond the pelvis is rare and has a poor prognosis. Data on primary treatment including systemic treatments for distant metastatic vulvar disease is limited due to rarity and lack of clinical trials. The purpose of this article is to present an atypical presentation of recurrent vulvar squamous cell carcinoma with metastasis to phalanges soft tissue and bone, clavicle and to the lungs and intracranial space.
外阴癌占美国新增癌症病例的0.3%。伴有盆腔以外疾病的转移性外阴癌很少见,预后较差。由于病例罕见且缺乏临床试验,关于包括远处转移性外阴疾病的全身治疗在内的初始治疗的数据有限。本文的目的是介绍一例复发性外阴鳞状细胞癌的非典型表现,其转移至指骨软组织、骨骼、锁骨、肺部及颅内。