Department of Ophthalmology, CF2 Clinical Hospital, Bucharest, Romania.
Department of ENT, "Titu Maiorescu" Faculty of Medicine, Bucharest, Romania.
Rom J Ophthalmol. 2024 Apr-Jun;68(2):191-197. doi: 10.22336/rjo.2024.36.
Lacrimal gland lymphomas are rare orbital tumors, constituting a minor fraction of all orbital and ocular adnexal malignancies. This case study presents an 83-year-old male with bilateral lacrimal gland tumors, more prominent in the left orbit, causing decreased visual acuity, red eye, excessive tearing, and diplopia. Initial ophthalmological evaluations and imaging suggested bilateral lacrimal gland lymphoma, confirmed by histopathology as diffuse large B-cell non-Hodgkin lymphoma of the MALT type. Due to the significant tumor size and risk of visual function loss, surgical intervention was performed, followed by corticosteroid therapy. Postoperatively, a marked improvement in symptoms and a reduction in tumor size were observed. This case underscores the importance of comprehensive diagnostic approaches, including clinical, imaging, and histopathological evaluations, highlighting the need for a multidisciplinary approach in managing rare orbital tumors like lacrimal gland lymphoma. The patient's postoperative and follow-up care included oncological management to monitor and ensure long-term disease control and patient well-being. RE = right eye, LE = left eye, CT = Computer tomography, MRI = Magnetic Resonance Imaging, TOD = intraocular pressure of right eye, TOS = intraocular pressure of left eye, US = ultrasound.
泪腺淋巴瘤是一种罕见的眼眶肿瘤，占所有眼眶和眼附属器恶性肿瘤的一小部分。本病例研究介绍了一位 83 岁男性，双侧泪腺有肿瘤，左眼更为明显，导致视力下降、眼红、溢泪和复视。最初的眼科评估和影像学检查提示双侧泪腺淋巴瘤，组织病理学证实为 MALT 型弥漫性大 B 细胞非霍奇金淋巴瘤。由于肿瘤体积大且存在视力丧失的风险，因此进行了手术干预，随后进行了皮质类固醇治疗。术后，症状明显改善，肿瘤体积缩小。本病例强调了综合诊断方法的重要性，包括临床、影像学和组织病理学评估，突出了在管理泪腺淋巴瘤等罕见眼眶肿瘤时需要多学科方法。患者的术后和随访护理包括肿瘤学管理，以监测和确保长期疾病控制和患者的健康。RE = 右眼，LE = 左眼，CT = 计算机断层扫描，MRI = 磁共振成像，TOD = 右眼眼压，TOS = 左眼眼压，US = 超声。
