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直肠乙状结肠部黄瘤内发生的管状腺瘤:一例报告

Tubular Adenoma Arising Within a Rectosigmoid Xanthoma: A Case Report.

作者信息

Coffey Kaley, Mateja Heather L, Bowers William, DeVito Peter

机构信息

General Surgery, Trumbull Regional Medical Center, Warren, USA.

General Surgery, American University of Antigua, Osbourn, ATG.

出版信息

Cureus. 2024 Jun 12;16(6):e62224. doi: 10.7759/cureus.62224. eCollection 2024 Jun.

DOI:10.7759/cureus.62224
PMID:39006590
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11244726/
Abstract

Colonic xanthomas are a rare finding, particularly when combined with a tubular adenoma in a single polyp. While transformation to malignancy is not thought to be higher than that of a tubular adenoma alone, there is still concern as to the pathophysiology of xanthoma formation within the colon and what that may mean for patient outcomes. Here, we present a patient undergoing a routine screening colonoscopy with the removal of a rectosigmoid polyp consistent with xanthoma and tubular adenoma histopathology. Proper follow-up for identification of possible metabolic derangements and increased colonic surveillance is recommended to mitigate the risk of further xanthoma or adenocarcinoma formation.

摘要

结肠黄色瘤是一种罕见的发现,尤其是当它与单个息肉中的管状腺瘤同时存在时。虽然人们认为其恶变率并不高于单纯的管状腺瘤,但对于结肠内黄色瘤形成的病理生理学以及这对患者预后可能意味着什么,仍存在担忧。在此,我们报告一名接受常规筛查结肠镜检查的患者,其切除了一个病理检查符合黄色瘤和管状腺瘤的直肠乙状结肠息肉。建议进行适当的随访以识别可能的代谢紊乱,并加强结肠监测,以降低进一步形成黄色瘤或腺癌的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2457/11244726/1184c0a23d31/cureus-0016-00000062224-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2457/11244726/1184c0a23d31/cureus-0016-00000062224-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2457/11244726/1184c0a23d31/cureus-0016-00000062224-i01.jpg

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本文引用的文献

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Adenoma arising from xanthoma in the transverse colon: a case report.横结肠黄色瘤引发的腺瘤:一例报告
Gastroenterol Rep (Oxf). 2023 Mar 15;11:goad013. doi: 10.1093/gastro/goad013. eCollection 2023.
2
Multiple, Large Colonic Xanthomas Presenting as Intestinal Obstruction.以肠梗阻为表现的多发性、大肠黄色瘤
Cureus. 2020 Jul 1;12(7):e8953. doi: 10.7759/cureus.8953.
3
A case of ascending colonic xanthoma presenting as a lateral spreading tumor.一例表现为侧向扩散性肿瘤的升结肠黄色瘤。
Intest Res. 2014 Apr;12(2):162-5. doi: 10.5217/ir.2014.12.2.162. Epub 2014 Apr 29.
4
Colorectal xanthomas with polypoid lesion: report of 25 cases.伴有息肉样病变的大肠黄色瘤:25例报告
APMIS. 2004 Jan;112(1):3-10. doi: 10.1111/j.1600-0463.2004.apm1120102.x.