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新型冠状病毒肺炎后亚急性甲状腺炎:一例无颈部疼痛的诊断挑战病例

Subacute Thyroiditis Following COVID-19: A Case of Diagnostic Challenge in the Absence of Neck Pain.

作者信息

Sakai Kan, Yonaha Tadahiro, Shinzato Takashi, Taira Takahiro

机构信息

General Internal Medicine, Nakagami Hospital, Okinawa, JPN.

出版信息

Cureus. 2024 Jun 11;16(6):e62203. doi: 10.7759/cureus.62203. eCollection 2024 Jun.

DOI:10.7759/cureus.62203
PMID:39006627
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11240006/
Abstract

This case report presents a 77-year-old woman who developed subacute thyroiditis following COVID-19. The patient exhibited atypical symptoms, including fever, fatigue, anorexia, significant weight loss, headaches, and palpitations, without the typical neck pain or tenderness associated with thyroiditis. One week later, a follow-up examination showed mild enlargement and tenderness of the thyroid. Laboratory tests indicated elevated thyroid hormone levels and suppressed thyroid-stimulating hormone. Ultrasonography revealed diffuse thyroid enlargement with poor blood flow, consistent with subacute thyroiditis. Despite the absence of typical neck pain, the diagnosis was supported by clinical, laboratory, and imaging findings. This case suggests the importance of considering subacute thyroiditis as a potential secondary condition following COVID-19, even in the absence of typical symptoms. Clinicians should consider that and perform thorough evaluations in patients with recent COVID-19 exposure and nonspecific symptoms.

摘要

本病例报告介绍了一名77岁女性,她在感染新冠病毒后患上了亚急性甲状腺炎。患者表现出非典型症状,包括发热、疲劳、厌食、显著体重减轻、头痛和心悸,没有与甲状腺炎相关的典型颈部疼痛或压痛。一周后,随访检查显示甲状腺轻度肿大并有压痛。实验室检查表明甲状腺激素水平升高,促甲状腺激素受到抑制。超声检查显示甲状腺弥漫性肿大,血流不佳,符合亚急性甲状腺炎。尽管没有典型的颈部疼痛,但临床、实验室和影像学检查结果支持这一诊断。该病例表明,即使没有典型症状,也应考虑亚急性甲状腺炎作为新冠病毒感染后的潜在继发病症。临床医生应考虑到这一点,并对近期接触过新冠病毒且有非特异性症状的患者进行全面评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a36/11240006/9473a44fd188/cureus-0016-00000062203-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a36/11240006/9473a44fd188/cureus-0016-00000062203-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a36/11240006/9473a44fd188/cureus-0016-00000062203-i01.jpg

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Autoimmune Thyroid Diseases.自身免疫性甲状腺疾病
Semin Nucl Med. 2024 Mar;54(2):219-236. doi: 10.1053/j.semnuclmed.2023.11.002. Epub 2023 Dec 2.
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Beyond Acute COVID-19: Investigating the Incidence of Subacute Thyroiditis in Long COVID-19 in Korea.
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Endocrinol Metab (Seoul). 2023 Aug;38(4):455-461. doi: 10.3803/EnM.2023.1711. Epub 2023 Aug 8.
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Subacute thyroiditis following COVID-19: A systematic review.COVID-19 后亚急性甲状腺炎:系统评价。
Front Endocrinol (Lausanne). 2023 Apr 5;14:1126637. doi: 10.3389/fendo.2023.1126637. eCollection 2023.
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COVID-19 and thyroid function: What do we know so far?COVID-19 与甲状腺功能:目前我们了解多少?
Front Endocrinol (Lausanne). 2022 Dec 19;13:1041676. doi: 10.3389/fendo.2022.1041676. eCollection 2022.
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