Devdhar Sarita, Gupta Vertika, Gautam Rashmi, Chaudhary Arun
Pathology, Noida International Institute of Medical Sciences, Greater Noida, IND.
Pathology, Saraswathi Institute of Medical Sciences, Hapur, IND.
Cureus. 2024 Jun 11;16(6):e62204. doi: 10.7759/cureus.62204. eCollection 2024 Jun.
Osseous metaplasia of the endometrium is a rare and intriguing pathological condition characterized by the presence of bony tissue within the endometrial cavity. This phenomenon can have significant clinical implications, particularly in the context of infertility. The etiology of osseous metaplasia remains unclear, although various hypotheses have been proposed, including chronic inflammation, dystrophic calcification, and residual embryonic tissue. Clinically, patients may present with secondary infertility, abnormal uterine bleeding, or pelvic pain. Diagnosis can be made based on ultrasonography and histopathological analysis of the endometrial tissue. Treatment typically involves the removal of the osseous tissue via hysteroscopy, which can lead to the restoration of normal endometrial function and potentially resolve infertility. Further research is needed to elucidate the etiological factors and optimize treatment protocols.
子宫内膜骨化生是一种罕见且引人关注的病理状况，其特征是子宫内膜腔内存在骨组织。这种现象可能具有重大临床意义，尤其是在不孕症的背景下。尽管已提出各种假说，包括慢性炎症、营养不良性钙化和残留胚胎组织，但骨化生的病因仍不清楚。临床上，患者可能表现为继发性不孕、异常子宫出血或盆腔疼痛。诊断可基于子宫内膜组织的超声检查和组织病理学分析。治疗通常包括通过宫腔镜切除骨组织，这可恢复正常的子宫内膜功能并可能解决不孕症。需要进一步研究以阐明病因因素并优化治疗方案。
