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乳房重建术后出现的罕见病症:坏疽性脓皮病。

A Rare Entity Developing After Breast Reconstruction: Pyoderma Gangrenosum.

作者信息

Yanıkoğlu Erkan, Ekinci Can, Kose Aydan A

机构信息

Plastic, Reconstructive and Esthetic Surgery, Osmangazi University School of Medicine, Eskişehir, TUR.

出版信息

Cureus. 2024 Jun 14;16(6):e62361. doi: 10.7759/cureus.62361. eCollection 2024 Jun.

DOI:10.7759/cureus.62361
PMID:39006718
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11246777/
Abstract

Pyoderma gangrenosum (PG) is a rare and persistent neutrophilic dermatosis with an unknown cause. The condition typically manifests clinically as a pustule or plaque that quickly evolves into a necrotic ulcer with undermined violet-colored margins. A surgical debridement might worsen the disease due to the pathergy phenomenon. This case report presents a 48-year-old woman who underwent a late breast reconstruction with a transverse rectus abdominis myocutaneous flap and was subsequently diagnosed with PG. The report details the delays in the diagnosis and management of the disease, providing a comprehensive account of the course of events.

摘要

坏疽性脓皮病(PG)是一种罕见的、持续存在的嗜中性皮肤病,病因不明。该病在临床上通常表现为脓疱或斑块,迅速发展为边缘呈紫罗兰色且呈潜行性的坏死性溃疡。由于同形反应现象,手术清创可能会使病情恶化。本病例报告介绍了一名48岁女性,她接受了腹直肌横形肌皮瓣晚期乳房重建术,随后被诊断为坏疽性脓皮病。该报告详细阐述了疾病诊断和治疗的延误情况,全面描述了事件的经过。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a04/11246777/00fd881d672e/cureus-0016-00000062361-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a04/11246777/a3fa1f5812a7/cureus-0016-00000062361-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a04/11246777/15f82ae33df9/cureus-0016-00000062361-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a04/11246777/b39d90274b48/cureus-0016-00000062361-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a04/11246777/00fd881d672e/cureus-0016-00000062361-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a04/11246777/a3fa1f5812a7/cureus-0016-00000062361-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a04/11246777/15f82ae33df9/cureus-0016-00000062361-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a04/11246777/b39d90274b48/cureus-0016-00000062361-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a04/11246777/00fd881d672e/cureus-0016-00000062361-i04.jpg

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本文引用的文献

1
Pyoderma Gangrenosum Mimicking Wound Infection after Breast Cancer Surgery.乳腺癌手术后酷似伤口感染的坏疽性脓皮病
J Breast Cancer. 2021 Aug;24(4):409-416. doi: 10.4048/jbc.2021.24.e25. Epub 2021 Apr 29.
2
Latest Advancements in Autologous Breast Reconstruction.自体乳房重建的最新进展。
Plast Reconstr Surg. 2021 Jan 1;147(1):111e-122e. doi: 10.1097/PRS.0000000000007480.
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Perioperative management of pyoderma gangrenosum.坏疽性脓皮病的围手术期处理。
J Am Acad Dermatol. 2020 Aug;83(2):369-374. doi: 10.1016/j.jaad.2020.01.002. Epub 2020 Jan 9.
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The Association of Age With Clinical Presentation and Comorbidities of Pyoderma Gangrenosum.年龄与坏疽性脓皮病临床表现和合并症的关系。
JAMA Dermatol. 2018 Apr 1;154(4):409-413. doi: 10.1001/jamadermatol.2017.5978.
5
Post Surgical Pyoderma Gangrenosum in flap surgery: diagnostic clues and treatment recommendations.皮瓣手术术后坏疽性脓皮病:诊断线索与治疗建议
Acta Chir Belg. 2017 Apr;117(2):69-76. doi: 10.1080/00015458.2016.1264729. Epub 2016 Dec 9.
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Postoperative Pyoderma Gangrenosum: A Clinical Review of Published Cases.术后坏疽性脓皮病:已发表病例的临床综述。
Mayo Clin Proc. 2016 Sep;91(9):1267-79. doi: 10.1016/j.mayocp.2016.05.001. Epub 2016 Jul 31.
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Treatment recommendations for pyoderma gangrenosum: an evidence-based review of the literature based on more than 350 patients.坏疽性脓皮病的治疗建议:基于350多名患者的文献循证综述
J Am Acad Dermatol. 2005 Aug;53(2):273-83. doi: 10.1016/j.jaad.2004.10.006.
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Atypical pyoderma gangrenosum after breast reduction.乳房缩小术后的非典型坏疽性脓皮病。
Aesthetic Plast Surg. 2003 Jul-Aug;27(4):328-31. doi: 10.1007/s00266-003-3017-y.
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Surgical management of pyoderma gangrenosum: case report and review.坏疽性脓皮病的外科治疗:病例报告及文献复习
Dermatol Surg. 2000 Nov;26(11):1063-6. doi: 10.1046/j.1524-4725.2000.0260111063.x.
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Pyoderma gangrenosum: a review of 86 patients.坏疽性脓皮病:86例患者的回顾
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