Department of Kinesiology, University of New Hampshire, Durham, NH, 03824, USA.
Geisel School of Medicine at Dartmouth, Dartmouth College, Hanover, NH, 03755, USA.
Adv Biol (Weinh). 2024 Oct;8(10):e2400068. doi: 10.1002/adbi.202400068. Epub 2024 Jul 15.
When low muscle mass and impaired strength and physical function coexist with excess adiposity, it is termed sarcopenic obesity (SO). Handgrip strength (HGS) is a predictor of disability and mortality. Asymmetry in HGS, particularly ≥ 10% strength differences between hands, may indicate neuromuscular dysfunction observable prior to declines in maximal strength are detectedand therefore could be incorporated to identify those at risk of physical limitations and SO. This study compares HGS values and asymmetry in older adults with excess adiposity and evaluates their relationships with physical function. Baseline data from two previous pilot weight loss studies in 85 older adults with body mass index values ≥ 30 kg m are included with measures of body composition, walking speed, and chair stand ability. Sixty-three participants met the criteria for SO. HGS correlated to gait speed (r = 0.22), distance walked (r = 0.40), chair stand time for 5 repetitions (r = 0.42) and during 30 s (r = 0.31). HGS asymmetry is only correlated to gait speed (r = 0.31) and there are no differences in physical function between those with and without asymmetry. Maximal HGS tests should continue to be used to screen for functional decline and disability.
当肌肉量减少、力量和身体功能受损与肥胖并存时，被称为肌少症性肥胖（SO）。握力（HGS）是残疾和死亡的预测指标。HGS 不对称，特别是双手之间的力量差异≥10%，可能表明在最大力量下降之前就已经出现了神经肌肉功能障碍，因此可以将其纳入识别那些有身体受限和 SO 风险的人的指标。本研究比较了肥胖老年人的 HGS 值和不对称性，并评估了它们与身体功能的关系。研究纳入了两项先前针对 85 名体重指数≥30 kg/m2 的超重老年人进行的减肥研究的基线数据，同时测量了身体成分、步行速度和椅子站立能力。63 名参与者符合 SO 的标准。HGS 与步行速度（r = 0.22）、行走距离（r = 0.40）、5 次重复的椅子站立时间（r = 0.42）和 30 秒的椅子站立时间（r = 0.31）相关。HGS 不对称仅与步行速度相关（r = 0.31），并且在有无不对称的人群之间，身体功能没有差异。最大 HGS 测试应继续用于筛查功能下降和残疾。
