J Am Dent Assoc. 2024 Sep;155(9):735-746. doi: 10.1016/j.adaj.2024.05.007. Epub 2024 Jul 14.
Sleep disturbances have been shown to result in considerable morbidity and mortality. It is important for dental clinicians to understand the neuroscience behind sleep disorders.
The authors conducted a search of the literature published from January 1990 through March 2024 of sleep medicine-related articles, with a focus on neuroscience. The authors prioritized articles about the science of sleep as related to dental medicine.
The authors found a proliferation of articles related to sleep neuroscience along with its implications in dental medicine. The authors also found that the intricate neuroscientific principles of sleep medicine are being investigated robustly. The salient features of, and the differences between, central and obstructive sleep apneas have been elucidated. Sleep genes, such as CRY, PER1, PER2, and CLOCK, and their relationship to cancer and neurodegeneration are also additions to this rapidly developing science.
The dental clinician has the potential to be the first to screen patients for possible sleep disorders and make prompt referrals to the appropriate medical professionals. This can be lifesaving as well as minimize potential future morbidity for the patient.
睡眠障碍已被证明会导致相当高的发病率和死亡率。牙医临床医生了解睡眠障碍背后的神经科学知识非常重要。
作者对睡眠医学相关文章进行了文献检索，这些文章发表于 1990 年 1 月至 2024 年 3 月，重点关注神经科学。作者优先选择了与牙科医学相关的睡眠科学的文章。
作者发现，与睡眠神经科学及其在牙科医学中的应用相关的文章大量涌现。作者还发现，睡眠医学中复杂的神经科学原理正在得到深入研究。中枢性和阻塞性睡眠呼吸暂停的显著特征及其差异已经阐明。睡眠基因，如 CRY、PER1、PER2 和 CLOCK，以及它们与癌症和神经退行性变的关系，也是这一快速发展的科学领域的新内容。
牙医临床医生有可能成为第一个筛查患者是否存在睡眠障碍并及时向适当的医疗专业人员转介的人。这不仅可以拯救生命，还可以最大限度地减少患者未来的潜在发病率。
